E 7010
- ₹6100 - ₹14800
- Product name: E 7010
- CAS: 141430-65-1
- MF: C18H17N3O4S
- MW: 371.41
- EINECS:256-495-9
- MDL Number:MFCD00910291
- Synonyms:E 7010;N-[2-(4-HYDROXYANILINO)PYRIDIN-3-YL]-4-METHOXYBENZENE-1-SULFONAMIDE;N-[2-[(4-Hydroxyphenyl)amino]-3-pyridyl]-4-methoxybenzenesulfonamide;BenzenesulfonaMide, N-[2-[(4-hydroxyphenyl)aMino]-3-pyridinyl]-4-Methoxy-;ABT-751 (E7010);N-(2-(4-hydroxyphenylamino)pyridin-3-yl)-4-methoxybenzenesulfonamide;ABT-751 (E;E7010(ABT-751)
2 prices
Selected condition:
Brand
- TCI Chemicals (India)
Package
- 10MG
- 50MG
- ManufacturerTCI Chemicals (India)
- Product numberA3169
- Product descriptionABT-751
- Packaging10MG
- Price₹6100
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberA3169
- Product descriptionABT-751
- Packaging50MG
- Price₹14800
- Updated2022-05-26
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | A3169 | ABT-751 | 10MG | ₹6100 | 2022-05-26 | Buy |
TCI Chemicals (India) | A3169 | ABT-751 | 50MG | ₹14800 | 2022-05-26 | Buy |
Properties
Melting point :162 °C(dec.)
Boiling point :551.0±60.0 °C(Predicted)
Density :1.427
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :insoluble in H2O; ≥18.55 mg/mL in DMSO; ≥25.53 mg/mL in EtOH with ultrasonic
form :powder to crystal
pka :7.86±0.40(Predicted)
color :White to Yellow to Orange
Boiling point :551.0±60.0 °C(Predicted)
Density :1.427
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :insoluble in H2O; ≥18.55 mg/mL in DMSO; ≥25.53 mg/mL in EtOH with ultrasonic
form :powder to crystal
pka :7.86±0.40(Predicted)
color :White to Yellow to Orange
Safety Information
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Description
ABT-751 is a tubulin polymerization inhibitor that binds to the colchicine binding site on β-tubulin (Ki = 3.3 μM). It inhibits tubulin polymerization in a concentration-dependent manner and inhibits growth of 26 human tumor cell lines (IC50s = 0.06-0.08 μg/ml). ABT-751 (100 mg/kg, p.o.) induces tumor regression in NB-1382 neuroblastoma, IRS56 rhabdomyosarcoma, and KT-6 Wilms mouse xenograft models. It also induces tumor endothelial cell retraction and reduces tumor perfusion, but not muscle perfusion, in a 9L rat glioma subcutaneous tumor model.More related product prices
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