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ChemicalBook > Product Catalogue >API >Synthetic Anti-infective Drugs >Antifungal Drugs >Econazole

Econazole

Econazole Structure
  • ₹0
  • Product name: Econazole
  • CAS: 27220-47-9
  • MF: C18H15Cl3N2O
  • MW: 381.68
  • EINECS:248-341-6
  • MDL Number:MFCD00800993
  • Synonyms:1-(2-((4-chlorophenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1h-imidazol ;1-(2,4-dichloro-beta-((p-chlorobenzyl)oxy)phenethyl)-imidazol ;1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1h-imidazole;ECONAZOLE;ECONAZOLUM;1-[2,4-Dichloro-β-[(p-chlorobenzyl)oxy]phenethyl]imidazole;1H-Imidazole, 1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-;Imidazole, 1-[2,4-dichloro-β-[(p-chlorobenzyl)oxy]phenethyl]- (8CI)
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :86.8°C
Boiling point :533.8±50.0 °C(Predicted)
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :Practically insoluble in water, very soluble in ethanol (96 per cent) and in methylene chloride.
pka :6.68±0.12(Predicted)
form :Solid
color :White to off-white
Water Solubility :0.37g/L(ambient temperature)
CAS DataBase Reference :27220-47-9(CAS DataBase Reference)
EPA Substance Registry System :Econazole (27220-47-9)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

antineoplastic, anti-estrogen.
Econazole (Spectazole) is a synthetic imidazole. Econazole blocks C-14 demethylation of sterols, interfering with the biosynthesis of ergosterol, which results in disorganization of the fungal plasma cell membrane and increased permeability. It is active against dermatophytes, yeast, P. orbiculare, Aspergillus, Cladosporium, and Sporothrix.

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