Genipin
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- ₹6700 - ₹50184.7
- Product name: Genipin
- CAS: 6902-77-8
- MF: C11H14O5
- MW: 226.23
- EINECS:636-196-5
- MDL Number:MFCD00888600
- Synonyms:Methyl (1R,2R,6S)-2-hydroxy-9-(hydroxymethyl)-3-oxabicyclo[4.3.0]nona-4,8-diene-5-carboxylate;cyclopenta(c)pyran-4-carboxylicacid,1,4a-alpha,5,7a-alpha-tetrahydro-1-hydrox ;GENIPIN;1,4a,5,7a-tetrahydro-1-hydroxy-7-(hydroxymethyl)-cyclopenta(c)pyran-4-carboxylic acid methyl ester;Methyl (1S,2R,6S)-2-hydroxy-9-(hydroxymethyl)-3-oxabicyclo[4.3.0]nona-4,8-diene-5-carboxylate;(1R)-1,4aα,5,7aα-Tetrahydro-1-hydroxy-7-hydroxymethylcyclopenta[c]pyran-4-carboxylic acid methyl ester;(1R)-1,4aα,5,7aα-Tetrahydro-1α-hydroxy-7-hydroxymethylcyclopenta[c]pyran-4-carboxylic acid methyl ester;Methyl (1S,2R,6S)-2-hydroxy-9-(hydroxymethyl)-3-oxabicyclo[4.3.0]nona-
4 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 25MG
- 100MG
- 125MG
- ManufacturerTCI Chemicals (India)
- Product numberG0458
- Product descriptionGenipin min. 97.0 %
- Packaging25MG
- Price₹6700
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberG0458
- Product descriptionGenipin min. 97.0 %
- Packaging100MG
- Price₹16800
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberG4796
- Product descriptionGenipin ≥98% (HPLC), powder
- Packaging125MG
- Price₹50184.7
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberG4796
- Product descriptionGenipin ≥98% (HPLC), powder
- Packaging25MG
- Price₹12546.18
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | G0458 | Genipin min. 97.0 % | 25MG | ₹6700 | 2022-05-26 | Buy |
| TCI Chemicals (India) | G0458 | Genipin min. 97.0 % | 100MG | ₹16800 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | G4796 | Genipin ≥98% (HPLC), powder | 125MG | ₹50184.7 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | G4796 | Genipin ≥98% (HPLC), powder | 25MG | ₹12546.18 | 2022-06-14 | Buy |
Properties
Melting point :118.0 to 123.0 °C
Boiling point :287.83°C (rough estimate)
Density :1.1230 (rough estimate)
refractive index :1.4720 (estimate)
storage temp. :Inert atmosphere,Room Temperature
solubility :DMSO: ≥25mg/mL
form :powder
pka :12.06±0.60(Predicted)
color :White to Almost white
λmax :240nm(MeOH)(lit.)
InChI :InChI=1S/C11H14O5/c1-15-10(13)8-5-16-11(14)9-6(4-12)2-3-7(8)9/h2,5,7,9,11-12,14H,3-4H2,1H3/t7-,9-,11-/m1/s1
InChIKey :AZKVWQKMDGGDSV-BCMRRPTOSA-N
SMILES :[C@@H]1(O)OC=C(C(OC)=O)[C@@]2([H])CC=C(CO)[C@@]12[H]
CAS DataBase Reference :6902-77-8(CAS DataBase Reference)
Boiling point :287.83°C (rough estimate)
Density :1.1230 (rough estimate)
refractive index :1.4720 (estimate)
storage temp. :Inert atmosphere,Room Temperature
solubility :DMSO: ≥25mg/mL
form :powder
pka :12.06±0.60(Predicted)
color :White to Almost white
λmax :240nm(MeOH)(lit.)
InChI :InChI=1S/C11H14O5/c1-15-10(13)8-5-16-11(14)9-6(4-12)2-3-7(8)9/h2,5,7,9,11-12,14H,3-4H2,1H3/t7-,9-,11-/m1/s1
InChIKey :AZKVWQKMDGGDSV-BCMRRPTOSA-N
SMILES :[C@@H]1(O)OC=C(C(OC)=O)[C@@]2([H])CC=C(CO)[C@@]12[H]
CAS DataBase Reference :6902-77-8(CAS DataBase Reference)
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Genipin is a compound isolated from Gardenis jasminoides Ellis fruits which acts as a cell permeable inhibitor of UCP2 (uncoupling protein 2). Increases glucose-stimulated insulin secretion, mitochondrial membrane potential and ATP levels in pancreatic island cells. Genipin has been shown to induce apoptosis and is a protein cross-linking agent. Genipin, at 5 μM, increases glucose-stimulated insulin secretion in isolated pancreatic islets chronically exposed to high levels of glucose. Genipin also exhibits anti-inflammatory and anti-angiogenic properties by inducing apoptosis in FaO rat hepatoma cells and human hepatocarcinoma Hep3B cells.More related product prices
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