GS967
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- Product name: GS967
- CAS: 1262618-39-2
- MF: C14H7F6N3O
- MW: 347.22
- EINECS:
- MDL Number:MFCD28385879
- Synonyms:GS967;6-(4-(trifluoroMethoxy)phenyl)-3-(trifluoroMethyl)-[1,2,4]triazolo[4,3-a]pyridine;GS 458967;GS458967;GS-458967;GS-967;GS 967;GS-458967; GS 458967; GS458967;GS967(GS-458967);GS967, >98%
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Properties
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥13.35 mg/mL in DMSO; ≥25.52 mg/mL in EtOH with ultrasonic
form :solid
pka :-0.41±0.50(Predicted)
color :White to off-white
storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥13.35 mg/mL in DMSO; ≥25.52 mg/mL in EtOH with ultrasonic
form :solid
pka :-0.41±0.50(Predicted)
color :White to off-white
Safety Information
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Description
Inhibition of cardiac late sodium current (late INa) is a strategy to suppress arrhythmias and sodium-dependent calcium overload associated with myocardial ischemia and heart failure. GS967 is a selective inhibitor of late INa that has been shown to suppress experimentally induced arrhythmias in rabbit myocytes and hearts. It can inhibit A. sulcata toxin II–induced late INa in ventricular myocytes and isolated hearts with IC50 values of 0.13 and 0.21 μM, respectively. GS967 causes minimal inhibition of the delayed-rectifier potassium current nor does it affect L- or T-type calcium channel currents, sodium-calcium exchanger currents, or a panel of 162 receptors, ion channels, transporters, and enzymes.More related product prices
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Suppliers and manufacturers
career henan chemical co
![6-(4-(trifluoroMethoxy)phenyl)-3-(trifluoroMethyl)-[1,2,4]triazolo[4,3-a]pyridine](https://img.chemicalbook.com/ProductImageEN/2019-9/small/52a74ed7-749b-4502-bb97-fa685facc639.jpg)
A.J Chemicals
ATK CHEMICAL COMPANY LIMITED
BOC Sciences
TargetMol Chemicals Inc.
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
ShenZhen Trendseen Biological Technology Co.,Ltd.
Aladdin Scientific
₹1.00 /1KG
6-(4-(trifluoroMethoxy)phenyl)-3-(trifluoroMethyl)-[1,2,4]triazolo[4,3-a]pyridine CAS:1262618-39-2
6-(4-(trifluoroMethoxy)phenyl)-3-(trifluoroMethyl)-[1,2,4]triazolo[4,3-a]pyridine CAS:1262618-39-2
