4-HYDROXY-2-[(1E)-[4-(1-METHYLETHYL)PHENYL]METHYLENE]HYDRAZIDE
![4-HYDROXY-2-[(1E)-[4-(1-METHYLETHYL)PHENYL]METHYLENE]HYDRAZIDE Structure](/CAS/GIF/101574-65-6.gif)
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- ₹10954.9 - ₹43126.8
- Product name: 4-HYDROXY-2-[(1E)-[4-(1-METHYLETHYL)PHENYL]METHYLENE]HYDRAZIDE
- CAS: 101574-65-6
- MF: C17H18N2O2
- MW: 282.34
- EINECS:
- MDL Number:MFCD00567155
- Synonyms:(E)-4-hydroxy-N'-(4-isopropylbenzylidene)benzohydrazide;4-Hydroxybenzoic acid 2-[[4-(1-methylethyl)phenyl]methylene]hydrazide;4-HYDROXY-2-[(1E)-[4-(1-METHYLETHYL)PHENYL]METHYLENE]HYDRAZIDE;2-[[4-(1-Methylethyl)phenyl]methylene]hydrazide 4-hydroxybenzoic acid;4-hydroxy-N'-(4-isopropylbenzylidene)benzohydrazide;CS-1084;Benzoic acid, 4-hydroxy-, 2-[[4-(1-methylethyl)phenyl]methylene]hydrazide;4-hydroxy-N'-(4-isopropylphenyl‐ methylidene)-benzohydrazide
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 10MG
- 50MG
- ManufacturerSigma-Aldrich(India)
- Product numberG6173
- Product descriptionGSK 4716 ≥98% (HPLC)
- Packaging10MG
- Price₹10954.9
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberG6173
- Product descriptionGSK 4716 ≥98% (HPLC)
- Packaging50MG
- Price₹43126.8
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | G6173 | GSK 4716 ≥98% (HPLC) | 10MG | ₹10954.9 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | G6173 | GSK 4716 ≥98% (HPLC) | 50MG | ₹43126.8 | 2022-06-14 | Buy |
Properties
Density :1.12
storage temp. :Inert atmosphere,2-8°C
solubility :DMSO: >10mg/mL
form :powder
pka :8.48±0.15(Predicted)
color :white to off-white
storage temp. :Inert atmosphere,2-8°C
solubility :DMSO: >10mg/mL
form :powder
pka :8.48±0.15(Predicted)
color :white to off-white
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
The estrogen-related receptors (ERRs) are orphan nuclear receptors with homology to the estrogen receptor family and are expressed in tissues with high metabolic demand. Binding of peroxisome proliferator-activated receptor γ-coactivator 1α (PGC-1α) to this class of receptors is known to potentiate ERR activity. GSK4716 is an ERRβ/γ agonist (IC50 = 2 μM) that can activate the receptor with similar potency as the protein ligand, PGC-1α. It is more than 50-fold selective for binding to ERRβ/γ compared with the estrogen receptors. This compound has been used to demonstrate the contribution of ERR receptor activity to the regulation of mitochondrial activity in skeletal muscle during exercise.Related product price
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₹14440 - GSK J1
₹11677.2-47552.4 - 101574-65-6
₹10954.9-43126.8
![4-HYDROXY-2-[(1E)-[4-(1-METHYLETHYL)PHENYL]METHYLENE]HYDRAZIDE](https://img.chemicalbook.com/ProductImageEN/2019-8/small/5cb209a9-e5a3-43fd-9135-752a720bab90.jpg){kind=small}