GSK J1
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- ₹11677.2 - ₹47552.4
- Product name: GSK J1
- CAS: 1373422-53-7
- MF: C22H23N5O2
- MW: 389.45
- EINECS:200-258-5
- MDL Number:MFCD22683851
- Synonyms:GSK J1;GSK-J1;N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-beta-alanine;GCK J1;3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(pyridin-2-yl)pyrimidin-4-yl)amino)propanoic acid;N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyriMidinyl]-|-alanine;Histone Lysine Demethylase Inhibitor VII, GSK-J1 ;Histone Lysine Demethylase Inhibitor VII, GSK-J1 - CAS 1373422-53-7 - Calbiochem
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML0709
- Product descriptionGSK-J1 ≥98% (HPLC)
- Packaging5MG
- Price₹11677.2
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0709
- Product descriptionGSK-J1 ≥98% (HPLC)
- Packaging25MG
- Price₹47552.4
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML0709 | GSK-J1 ≥98% (HPLC) | 5MG | ₹11677.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML0709 | GSK-J1 ≥98% (HPLC) | 25MG | ₹47552.4 | 2022-06-14 | Buy |
Properties
Boiling point :608.9±55.0 °C(Predicted)
Density :1.292±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble15mg/mL, clear
form :powder
pka :4.20±0.10(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase? as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChIKey :AVZCPICCWKMZDT-UHFFFAOYSA-N
Density :1.292±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble15mg/mL, clear
form :powder
pka :4.20±0.10(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase? as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChIKey :AVZCPICCWKMZDT-UHFFFAOYSA-N
Safety Information
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Description
GSK-J1 (1373422-53-7) is a potent and selective inhibitor of jumonji H3K27 histone demethylases JMJD3 and UTX (IC50 = 60 nM, human JMJD3). This is the first known inhibitor selective for the H3K27me3-specific JMJ subfamily which binds to the active catalytic site of the enzyme. The COOH group confers cell impermeability and as such GSK-J1 is useful as a standard in in vitro assays. A cell permeable ethyl ester analog is also available, see GSK-J4 (cat.# 10-1394).More related product prices
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