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GSK591

GSK591 Structure
  • ₹11073.98 - ₹44566.53
  • Product name: GSK591
  • CAS: 1616391-87-7
  • MF: C22H28N4O2
  • MW: 380.48
  • EINECS:-0
  • MDL Number:MFCD30187524
  • Synonyms:GSK591 (EPZ-015866);EPZ015866;GSK591(EPZ015866,GSK3203591);EPZ015866(GSK591);EPZ015866,GSK3203591;GSK591;GSK3203591(EPZ015866);EPZ-015866;EPZ 015866;GSK-591;GSK 591;GSK3203591;GSK-3203591;GSK 3203591
Price2 Properties Safety Information Description
2 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1751
  • Product descriptionGSK591 ≥97% (HPLC)
  • Packaging5MG
  • Price₹11073.98
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1751
  • Product descriptionGSK591 ≥97% (HPLC)
  • Packaging25MG
  • Price₹44566.53
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML1751 GSK591 ≥97% (HPLC) 5MG ₹11073.98 2022-06-14 Buy
Sigma-Aldrich(India) SML1751 GSK591 ≥97% (HPLC) 25MG ₹44566.53 2022-06-14 Buy

Properties

Boiling point :648.4±55.0 °C(Predicted)
Density :1.252±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :≥38 mg/mL in DMSO; insoluble in H2O; ≥15.4 mg/mL in EtOH
form :powder
pka :13.54±0.46(Predicted)
color :white to beige

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

GSK591 is a chemical probe of PRMT5 (protein arginine methyltransferase 5), which plays a key role in various biological processes. PRMT5 is related to many human diseases including certain cancers like mantle cell lymphoma (MCL). Therefore, GSK591 is a useful tool for testing biological and therapeutic hypotheses. Study has shown that it can potential inhibit the PRMT5/MEP50 complex and symmetric arginine methylation of SMD3. 

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