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2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid

2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid Structure
  • ₹14418.9 - ₹58054.48
  • Product name: 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid
  • CAS: 890842-28-1
  • MF: C25H22N2O2
  • MW: 382.45
  • EINECS:
  • MDL Number:MFCD12828779
  • Synonyms:GSK650394 (Free base);2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid;GSK 650394;SGK inhibitor GS650394;CS-1142;Benzoic acid, 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-;6-O-α-D-Glucopyranosyl-D-glucose
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0773
  • Product descriptionGSK-650394 ≥98% (HPLC)
  • Packaging5MG
  • Price₹14418.9
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0773
  • Product descriptionGSK-650394 ≥98% (HPLC)
  • Packaging25MG
  • Price₹58054.48
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0773 GSK-650394 ≥98% (HPLC) 5MG ₹14418.9 2022-06-14 Buy
Sigma-Aldrich(India) SML0773 GSK-650394 ≥98% (HPLC) 25MG ₹58054.48 2022-06-14 Buy

Properties

storage temp. :room temp
solubility :DMSO: soluble20mg/mL, clear
form :powder
color :white to beige

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

GSK650394 is an inhibitor of serum- and glucocorticoid-regulated kinase (IC50s = 62 and 103 nM for SGK1 and SGK2, respectively). It demonstrates greater than 30-fold selectivity for SGK1 over Akt and other related kinases. GSK650394 can inhibit the androgen-stimulated growth of human prostate carcinoma LNCaP cells with an IC50 value of ~ 1 μM.