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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Antihypertensive drugs >GUANFACINE HCL

GUANFACINE HCL

GUANFACINE HCL Structure
  • ₹6300.15 - ₹29400
  • Product name: GUANFACINE HCL
  • CAS: 29110-48-3
  • MF: C9H9Cl2N3O.ClH
  • MW: 282.55
  • EINECS:249-443-3
  • MDL Number:MFCD00798230
  • Synonyms:bs100-141 ;estulic ;lon798 ;n-(aminoiminomethyl)-2,6-dichlorobenzeneacetamidehydrochloride ;n-(aminoiminomethyl)-2,6-dichloro-benzeneacetamidmonohydrochloride ;n-amidino-2-(2,6-dichlorophenyl)acetamidehydrochloride ;N (AMINOIMINOMETHYL)-2,6-DICHLOROBENZENEACETAMIDE HYDROCHLORIDE SALT;[(2,6-DICHLOROPHENYL)ACETYL]GUANIDINE HYDROCHLORIDE
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 100MG
  • 500MG
  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberG0414
  • Product descriptionGuanfacine Hydrochloride
  • Packaging100MG
  • Price₹9800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberG0414
  • Product descriptionGuanfacine Hydrochloride
  • Packaging1G
  • Price₹29400
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberG1043
  • Product descriptionGuanfacine hydrochloride ≥98% (HPLC)
  • Packaging10MG
  • Price₹6300.15
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1751
  • Product descriptionGuanfacine hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price₹15198.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberG1043
  • Product descriptionGuanfacine hydrochloride ≥98% (HPLC)
  • Packaging50MG
  • Price₹28134.18
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) G0414 Guanfacine Hydrochloride 100MG ₹9800 2022-05-26 Buy
TCI Chemicals (India) G0414 Guanfacine Hydrochloride 1G ₹29400 2022-05-26 Buy
Sigma-Aldrich(India) G1043 Guanfacine hydrochloride ≥98% (HPLC) 10MG ₹6300.15 2022-06-14 Buy
Sigma-Aldrich(India) PHR1751 Guanfacine hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material 500MG ₹15198.3 2022-06-14 Buy
Sigma-Aldrich(India) G1043 Guanfacine hydrochloride ≥98% (HPLC) 50MG ₹28134.18 2022-06-14 Buy

Properties

Melting point :215-217℃
RTECS :CY1481000
storage temp. :Inert atmosphere,Room Temperature
solubility :H2O: 12 mg/mL at 60 °C, soluble
form :Solid
color :white
Merck :14,4561
Stability :Hygroscopic
InChIKey :DGFYECXYGUIODH-UHFFFAOYSA-N
CAS DataBase Reference :29110-48-3(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P321 Specific treatment (see … on this label).
P405 Store locked up.

Description

Guanfacine hydrochloride, a centrally acting anti-hypertensive agent, has been reported to be a specific α2A-AR adrenoceptor agonist. Activation of these α2A-AR adrenoreceptors has been shown to cause a decrease in blood pressure in vitro. Additional studies suggest that Guanfacine hydrochloride plays a role in solute/sodium osmoregulation and excretion.

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