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GW 3965 HYDROCHLORIDE

GW 3965 HYDROCHLORIDE Structure
  • ₹15523.05 - ₹61962.3
  • Product name: GW 3965 HYDROCHLORIDE
  • CAS: 405911-17-3
  • MF: C33H31ClF3NO3.HCl
  • MW: 0
  • EINECS:
  • MDL Number:MFCD08276920
  • Synonyms:3-[3-[n-(2-chloro-3-trifluoromethylbenzyl)-(2,2-diphenylethyl)amino]propyloxy]phenylacetic acid hydrochloride;3-[3-[n-(2-chloro-3-trifluoroMethylbenzyl)-(2,2-di…;GW3965 HCl;2-[3-[3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]propoxy]phenyl]acetic acid hydrochloride;GW3965 hydrochloride, >=98%;Benzeneacetic acid, 3-[3-[[[2-chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]-, hydrochloride;GW3965 HCl Salt;3-[3-[[[2-Chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]benzeneacetic acid hydrochloride
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberG6295
  • Product descriptionGW3965 hydrochloride ≥98% (HPLC), powder
  • Packaging5MG
  • Price₹15523.05
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberG6295
  • Product descriptionGW3965 hydrochloride ≥98% (HPLC), powder
  • Packaging25MG
  • Price₹61962.3
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) G6295 GW3965 hydrochloride ≥98% (HPLC), powder 5MG ₹15523.05 2022-06-14 Buy
Sigma-Aldrich(India) G6295 GW3965 hydrochloride ≥98% (HPLC), powder 25MG ₹61962.3 2022-06-14 Buy

Properties

storage temp. :Store at -20°C
solubility :DMSO: ≥20mg/mL
form :powder
color :white
InChIKey :NMPUWJFHNOUNQU-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The liver X receptors, LXRα and LXRβ, are nuclear receptors that act as ligand-dependent transcription factors. They modulate cholesterol, fatty acids, and glucose homeostasis. GW 3965 is an orally-active agonist of LXRα and LXRβ, activating the human isoforms with EC50 values of 190 and 30 nM, respectively. It alters LXR-regulated gene expression in mice and rats, affecting pathways related to glucose and lipid metabolism. GW 3965 also affects inflammation and pressor responses through LXRα and LXRβ.

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GW 3965 HYDROCHLORIDE CAS:405911-17-3
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