T0070907
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- ₹19116.95 - ₹70925.4
- Product name: T0070907
- CAS: 313516-66-4
- MF: C12H8ClN3O3
- MW: 277.66
- EINECS:
- MDL Number:MFCD00121849
- Synonyms:2-CHLORO-5-NITRO-N-4-PYRIDINYLBENZAMIDE;2-CHLORO-5-NITRO-N-(4-PYRIDYL)BENZAMIDE;T 0070907;N1-(4-PYRIDYL)-2-CHLORO-5-NITROBENZAMIDE;BenzaMide, 2-chloro-5-nitro-N-4-pyridinyl-;T0070907 - CAS 313516-66-4 - Calbiochem;CS-2314;T0070907 (T-0070907
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberT8703
- Product descriptionT0070907 ≥98% (HPLC)
- Packaging5MG
- Price₹19116.95
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberT8703
- Product descriptionT0070907 ≥98% (HPLC)
- Packaging25MG
- Price₹70925.4
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | T8703 | T0070907 ≥98% (HPLC) | 5MG | ₹19116.95 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T8703 | T0070907 ≥98% (HPLC) | 25MG | ₹70925.4 | 2022-06-14 | Buy |
Properties
Melting point :>184°C (dec.)
Density :1.498
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
form :White solid
color :white
Water Solubility :Soluble in DMSO at 10mg/ml. Insoluble in water.
Sensitive :Light Sensitive
Density :1.498
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
form :White solid
color :white
Water Solubility :Soluble in DMSO at 10mg/ml. Insoluble in water.
Sensitive :Light Sensitive
Safety Information
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Description
The peroxisome proliferator-activated receptor-γ (PPARγ) is the nuclear receptor responsible for transducing the therapeutic activity of the thiazolidinediones (TZDs). TZDs are a group of structurally related synthetic PPARγ receptor agonists with antidiabetic actions in vivo. There are many PPARγ agonists, including 15-deoxy-Δ12,14-prostaglandin J2 and azelaoyl PAF, which are naturally derived. However, only a few antagonists have been reported. T0070907 is a potent and selective antagonist of the human PPARγ with an apparent IC50 of 1 nM for the binding inhibition of rosiglitazone, a reference TZD. T0070907 covalently binds to Cys313 of PPARγ, inducing conformational changes that block the recruitment of transcriptional cofactors to the PPARγ/RXR heterodimer.Related product price
- Rosiglitazone maleate
₹14418.9 - 188591-46-0
₹16460-68901.13 - SB 431542
₹7400-17947.85
