Galanthamine
- ₹0
- Product name: Galanthamine
- CAS: 357-70-0
- MF: C17H21NO3
- MW: 287.35
- EINECS:609-175-3
- MDL Number:MFCD00867189
- Synonyms:GALANTHAMINE;GALANTHAMINE HYDROCHLORIDE;(4as,6r,8as)-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6h-benzofuro[3a,3,2-ef][2]benzazepin-6-ol;6H-Benzofuro(3a,3,2-ef)(2)benzazepin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, (4aS-(4aalpha,6beta,8aR*))-;6h-benzofuro(3a,3,2-ef)(2)benzazepin-6-ol,4a,5,9,10,11,12-hexahydro-3-methox ;Jilkon;Lycoremin;Lycoremine
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Properties
Melting point :119-1210C
alpha :D20 -118.8° (c = 1.378 in ethanol)
Boiling point :429.65°C (rough estimate)
Density :1.0662 (rough estimate)
refractive index :1.5022 (estimate)
storage temp. :Sealed in dry,Room Temperature
solubility :≥14.37 mg/mL in DMSO; ≥14.43 mg/mL in H2O with gentle warming; ≥45 mg/mL in EtOH with gentle warming
form :Powder
pka :pKa 8.32 (Uncertain)
color :White to off-white
CAS DataBase Reference :357-70-0(CAS DataBase Reference)
NIST Chemistry Reference :Galantamin(357-70-0)
alpha :D20 -118.8° (c = 1.378 in ethanol)
Boiling point :429.65°C (rough estimate)
Density :1.0662 (rough estimate)
refractive index :1.5022 (estimate)
storage temp. :Sealed in dry,Room Temperature
solubility :≥14.37 mg/mL in DMSO; ≥14.43 mg/mL in H2O with gentle warming; ≥45 mg/mL in EtOH with gentle warming
form :Powder
pka :pKa 8.32 (Uncertain)
color :White to off-white
CAS DataBase Reference :357-70-0(CAS DataBase Reference)
NIST Chemistry Reference :Galantamin(357-70-0)
Safety Information
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Description
Galantamine is an alkaloid originally isolated from the bulbs and flowers of various Galanthus species. It allosterically potentiates nicotinic acetylcholine receptors, as well as inhibits acetylcholinesterase (IC50 = 636-2010 nM), thereby promoting acetylcholine activity in the brain. Galantamine has been used in the clinical treatment of vascular dementia and Alzheimer’s disease symptoms and as a nootropic for other cognitive impairments.More related product prices
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