INK1117
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- ₹0
- Product name: INK1117
- CAS: 1268454-23-4
- MF: C19H17N5O3
- MW: 363.37
- EINECS:
- MDL Number:
- Synonyms:Methanone, [6-(2-aMino-5-benzoxazolyl)iMidazo[1,2-a]pyridin-3-yl]-4-Morpholinyl-;INK-1117 MLN1117;MLN1117;MLN1117 (INK1117);[6-(2-Amino-5-benzoxazolyl)imidazo[1,2-a]pyridin-3-yl]-4-morpholinylmethanone;[6-(2-amino-1,3-benzoxazol-5-yl)imidazo[1,2-a]pyridin-3-yl]-morpholin-4-ylmethanone;methyl 6-((5-((3-(trifluoromethyl)phenyl)carbamoyl)naphthalen-2-yl)oxy)pyrimidine-4-carboxylate;TAK-117(INK1117,MLN1117)
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
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Properties
Density :1.55±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≤1mg/ml in DMSO;0.25mg/ml in dimethyl formamide
form :crystalline solid
pka :4.75±0.50(Predicted)
color :White to gray
storage temp. :Store at -20°C
solubility :≤1mg/ml in DMSO;0.25mg/ml in dimethyl formamide
form :crystalline solid
pka :4.75±0.50(Predicted)
color :White to gray
Safety Information
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Description
INK1117 is an inhibitor of phosphoinositide 3-kinase α (PI3Kα) that is selective for p110α in vitro (IC50 = 15 nM for PI3Kα vs. >1 μM for other isoforms, as well as for mTOR) and in cells when used at 1 μM. It blocks signaling to Akt and inhibits growth of cancer cells harboring wild-type or mutated p110α. INK1117 does not interfere with B cell proliferation or NK cell maturation and survival.More related product prices
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Suppliers and manufacturers
A.J Chemicals
ATK CHEMICAL COMPANY LIMITED
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Wuhan Topule Biopharmaceutical Co., Ltd