Isradipine
|
- ₹11600 - ₹62785
- Product name: Isradipine
- CAS: 75695-93-1
- MF: C19H21N3O5
- MW: 371.39
- EINECS:630-420-5
- MDL Number:MFCD00153820
- Synonyms:PN-200-110;Presca;Prescal;4-(4-Benzofurazanyl)-2，6-dimethyl-1，4-dihydro-3，5-pyridinedicarboxylic acid methyl 1-methylethyl ester;4-(4-Benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic [chemical name] acid methyl 1-methylethyl ester;Dynacrine;Iomir;Rebfiden
4 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 5MG
- 10MG
- 25MG
- ManufacturerTCI Chemicals (India)
- Product numberI0876
- Product descriptionIsradipine
- Packaging25MG
- Price₹11600
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number5.08507
- Product descriptionIsradipine - CAS 75695-93-1 - Calbiochem A voltage gated calcium channel gating inhibitor of the dihydropyridine class.
- Packaging10MG
- Price₹12940
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberI6658
- Product descriptionIsradipine ≥98% (HPLC), solid
- Packaging5MG
- Price₹17406.6
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberI6658
- Product descriptionIsradipine ≥98% (HPLC), solid
- Packaging25MG
- Price₹62785
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | I0876 | Isradipine | 25MG | ₹11600 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | 5.08507 | Isradipine - CAS 75695-93-1 - Calbiochem A voltage gated calcium channel gating inhibitor of the dihydropyridine class. | 10MG | ₹12940 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | I6658 | Isradipine ≥98% (HPLC), solid | 5MG | ₹17406.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | I6658 | Isradipine ≥98% (HPLC), solid | 25MG | ₹62785 | 2022-06-14 | Buy |
Properties
Melting point :166-1680C
Boiling point :501.9±60.0 °C(Predicted)
Density :1.249±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ~26 mg/mL
form :solid
pka :2.56±0.70(Predicted)
color :yellow
Merck :14,5240
BCS Class :2/4
Stability :Stable for 2 years from date of purchsae as supplied. Protect from moisture. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey :HMJIYCCIJYRONP-UHFFFAOYSA-N
CAS DataBase Reference :75695-93-1(CAS DataBase Reference)
NIST Chemistry Reference :Isradipine(75695-93-1)
Boiling point :501.9±60.0 °C(Predicted)
Density :1.249±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ~26 mg/mL
form :solid
pka :2.56±0.70(Predicted)
color :yellow
Merck :14,5240
BCS Class :2/4
Stability :Stable for 2 years from date of purchsae as supplied. Protect from moisture. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey :HMJIYCCIJYRONP-UHFFFAOYSA-N
CAS DataBase Reference :75695-93-1(CAS DataBase Reference)
NIST Chemistry Reference :Isradipine(75695-93-1)
Safety Information
| Symbol(GHS): |
|
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | ||||||||||||||
| Hazard statements: |
|
||||||||||||||
| Precautionary statements: |
|
Description
Isradipine is a selective L-type calcium channel blocker with long-acting antihypertensive activity. It demonstrates an EC50 value of 1.4 nM for relaxation of depolarization-induced contractions of rabbit aorta and an EC25 value of 0.45 nM for reduction in rate of spontaneously beating guinea pig right atria. By suppressing calcium influx into the cytoplasm and Cav1.2 expression, isradipine has been shown to attenuate β-amyloid oligomer toxicity in an in vitro model of Alzheimer’s disease.Related product price
- Dimethyl carbonate
₹520-70254.25 - Dimethyl sulfoxide
₹802.14-1456730.01 - Dimethyl sebacate
₹1800-19820.58