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JNJ-10198409

JNJ-10198409 Structure
  • ₹19050 - ₹78719.4
  • Product name: JNJ-10198409
  • CAS: 627518-40-5
  • MF: C18H16FN3O2
  • MW: 325.34
  • EINECS:
  • MDL Number:MFCD11045292
  • Synonyms:PDGFR Tyrosine Kinase Inhibitor IV;JNJ-10198409;Indeno[1,2-c]pyrazol-3-amine, N-(3-fluorophenyl)-1,4-dihydro-6,7-dimethoxy-;RWJ 540973, 3-Fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamine, N-(3-fluorophenyl)-2,4-dihydro-6,7-dimethoxy-Indeno[1,2-c]pyrazol-3-amine;JNJ-10198409, Free Base;3-Fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamine;N-(3-fluorophenyl)-2,4-dihydro-6,7-dimethoxy-Indeno[1,2-c]pyrazol-3-amine;RWJ 540973
Price3 Properties Safety Information Description
3 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberJ4649
  • Product descriptionJNJ-10198409 ≥98% (HPLC), solid
  • Packaging5MG
  • Price₹78719.4
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberJ4649
  • Product descriptionJNJ-10198409 ≥98% (HPLC), solid
  • Packaging1MG
  • Price₹19658.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number521233
  • Product descriptionPDGFR Tyrosine Kinase Inhibitor IV - CAS 627518-40-5 - Calbiochem
  • Packaging1MG
  • Price₹19050
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) J4649 JNJ-10198409 ≥98% (HPLC), solid 5MG ₹78719.4 2022-06-14 Buy
Sigma-Aldrich(India) J4649 JNJ-10198409 ≥98% (HPLC), solid 1MG ₹19658.2 2022-06-14 Buy
Sigma-Aldrich(India) 521233 PDGFR Tyrosine Kinase Inhibitor IV - CAS 627518-40-5 - Calbiochem 1MG ₹19050 2022-06-14 Buy

Properties

Melting point :171-173.5 °C
Boiling point :528.8±50.0 °C(Predicted)
Density :1.366±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMSO: >10mg/mL
form :solid
pka :14.01±0.20(Predicted)
color :off-white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

PDGFR Tyrosine Kinase Inhibitor IV is a indenopyrazole compound that displays potent antiproliferative properties in human tumor cell lines. It acts as a reversible ATP-competitive inhibitor of PDGFR but exhibits less actibity towards Lck, c-Src, and Fyn while exhibiting little to no inhibition toward VEGFR, HER-2, Cdk's-1,-2,-4 &-7, bFGFR-1 and EGFR. PDGFR Tyrosine Kinase Inhibitor IV is cell-permeable. PDGFR Tyrosine Kinase Inhibitor IV is an inhibitor of c-Abl, PDGFR-α and PDGFR-β.

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