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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Ubiquitin >E2 conjugating inhibitors >NSC697923

NSC697923

NSC697923 Structure
  • ₹7144.5 - ₹26034.13
  • Product name: NSC697923
  • CAS: 343351-67-7
  • MF: C11H9NO5S
  • MW: 267.25786
  • EINECS:
  • MDL Number:MFCD01925132
  • Synonyms:Furan, 2-[(4-Methylphenyl)sulfonyl]-5-nitro-;NSC697923;2-[(4-Methylphenyl)sulfonyl]-5-nitrofuran;2-Nitro-5-tosylfuran;2-Nitro-5-(toluene-4-sulfonyl)-furan;2-[(4-Methylphenyl)sulfonyl]-5-nitrofur;NSC697923 USP/EP/BP
3 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0618
  • Product descriptionNSC697923 ≥98% (HPLC)
  • Packaging5MG
  • Price₹7144.5
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number662107
  • Product descriptionUbcH13 Inhibitor, NSC697923 - CAS 343351-67-8 - Calbiochem The UbcH13 Inhibitor, NSC697923 controls the biological activity of UbcH13. This small molecule/inhibitor is primarily used for Protease Inhibitors ap
  • Packaging25MG
  • Price₹16090
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0618
  • Product descriptionNSC697923 ≥98% (HPLC)
  • Packaging25MG
  • Price₹26034.13
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0618 NSC697923 ≥98% (HPLC) 5MG ₹7144.5 2022-06-14 Buy
Sigma-Aldrich(India) 662107 UbcH13 Inhibitor, NSC697923 - CAS 343351-67-8 - Calbiochem The UbcH13 Inhibitor, NSC697923 controls the biological activity of UbcH13. This small molecule/inhibitor is primarily used for Protease Inhibitors ap 25MG ₹16090 2022-06-14 Buy
Sigma-Aldrich(India) SML0618 NSC697923 ≥98% (HPLC) 25MG ₹26034.13 2022-06-14 Buy

Properties

Melting point :124-126°C
Boiling point :443.8±40.0 °C(Predicted)
Density :1.416±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

NSC 697923 is a selective inhibitor of the E2 ubiquitin-conjugating enzyme Ubc13 when heterodimerized with Uev1A, blocking polyubiquitin chain formation at concentrations of 0.5 to 2 μM in vitro. It also inhibits NF-κB activation by PMA and other agonists, presumably through its effects on Ubc13. NSC 697923 blocks proliferation and induces apoptosis in diffuse large B cell lymphoma and neuroblastoma cells. It has antitumor efficacy in vivo in neuroblastoma orthotopic xenografts, when given intraperitoneally.