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ChemicalBook > Product Catalogue >API >Digestive system drugs >Laxatives and Antidiarrheal Medicines >Loperamide hydrochloride

Loperamide hydrochloride

Loperamide hydrochloride Structure
  • ₹5564.05 - ₹58065.3
  • Product name: Loperamide hydrochloride
  • CAS: 34552-83-5
  • MF: C29H34Cl2N2O2
  • MW: 513.5
  • EINECS:252-082-4
  • MDL Number:MFCD00058581
  • Synonyms:blox ;butyramidehcl ;dissenten ;fortasec ;imosec ;LABOTEST-BB LT00134703;LOSERAMIN;LOPERAMIDE HYDROCHLORIDE
Price8 Properties Safety Information Description
8 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • Sigma-Aldrich

Package

  • 100MG
  • 1G
  • 5G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberL0154
  • Product descriptionLoperamide Hydrochloride
  • Packaging5G
  • Price₹9800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberL0154
  • Product descriptionLoperamide Hydrochloride
  • Packaging25G
  • Price₹16000
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberL4762
  • Product descriptionLoperamide hydrochloride
  • Packaging25G
  • Price₹58065.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberL4762
  • Product descriptionLoperamide hydrochloride
  • Packaging5G
  • Price₹14570.45
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number5.08162
  • Product descriptionLoperamide Hydrochloride - CAS 34552-83-5 - Calbiochem
  • Packaging1G
  • Price₹10550.01
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1162
  • Product descriptionLoperamide hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹9753.33
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number34014
  • Product descriptionLoperamide hydrochloride VETRANAL?, analytical standard
  • Packaging100MG
  • Price₹5564.05
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number34014
  • Product descriptionLoperamide hydrochloride VETRANAL?, analytical standard
  • Packaging100MG
  • Price₹5564.05
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) L0154 Loperamide Hydrochloride 5G ₹9800 2022-05-26 Buy
TCI Chemicals (India) L0154 Loperamide Hydrochloride 25G ₹16000 2022-05-26 Buy
Sigma-Aldrich(India) L4762 Loperamide hydrochloride 25G ₹58065.3 2022-06-14 Buy
Sigma-Aldrich(India) L4762 Loperamide hydrochloride 5G ₹14570.45 2022-06-14 Buy
Sigma-Aldrich(India) 5.08162 Loperamide Hydrochloride - CAS 34552-83-5 - Calbiochem 1G ₹10550.01 2022-06-14 Buy
Sigma-Aldrich(India) PHR1162 Loperamide hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹9753.33 2022-06-14 Buy
Sigma-Aldrich(India) 34014 Loperamide hydrochloride VETRANAL?, analytical standard 100MG ₹5564.05 2022-06-14 Buy
Sigma-Aldrich 34014 Loperamide hydrochloride VETRANAL?, analytical standard 100MG ₹5564.05 2022-06-14 Buy

Properties

Melting point :223-225°C
Density :1.1905 (rough estimate)
refractive index :1.6100 (estimate)
storage temp. :2-8°C
solubility :Slightly soluble in water, freely soluble in ethanol (96 per cent) and in methanol.
pka :8.66(at 25℃)
form :Solid
color :White to Almost white
Merck :14,5571
CAS DataBase Reference :34552-83-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:

Description

Loperamide is an opiate which potently and selectively activates μ opioid receptors (Ki = 0.16 nM) exclusively in the periphery. Loperamide is an opiate which potently and selectively activates μ opioid receptors (Ki = 0.16 nM) exclusively in the periphery. It is a much weaker agonist of the δ opiod receptor (Ki = 50 nM). Through its actions in the gut wall, loperamide has antidiarrheal action by increasing transit time and by altering intestinal transport of water and electrolytes. It also blocks voltage-sensitive sodium channels (IC50 = 270 nM) and high voltage-activated calcium channels (IC50 = 900 nM), presumably through an inhibitory effect on calmodulin. Loperamide is comparable to morphine in blocking peripheral pain in rats.

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TAGOOR LABORATORIES PVT LTD Jigs Chemical ltd ANWITA APIS MOLECRAFT LIFE SCIENCES PVT LTD Vamsi Labs Ltd Ralington Pharma Lanz Labs Pvt Ltd Fleming Laboratories Ltd Besil Chem LLP Lake Chemicals Pvt Ltd