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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >MK-4827 (tosylate)

MK-4827 (tosylate)

MK-4827 (tosylate) Structure
  • ₹0
  • Product name: MK-4827 (tosylate)
  • CAS: 1038915-73-9
  • MF: C26H28N4O4S
  • MW: 492.58992
  • EINECS:
  • MDL Number:MFCD28167748
  • Synonyms:Niraparib TsOH;niraparib p-toluenesulfonate;MK-4827(Niraparib) tosylate;MK-4827 (tosylate);(3S)-3-[4-[7-(Aminocarbonyl)-2H-indazol-2-yl]phenyl]piperidine tosylate;MK-4827, Niraparib TsOH salt;Niraparib(MK-4827) tosylate;NIRAPARIB TOSYLATE;MK 4827 TOSYLATE;MK4827 TOSYLATE
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :>142oC (dec.)
storage temp. :-20°C Freezer
solubility :Methanol (Slightly)
form :Solid
color :Off-White to Pale Yellow
InChIKey :LCPFHXWLJMNKNC-XOIICWPPNA-N
SMILES :S(C1C=CC(C)=CC=1)(O)(=O)=O.C(C1=CC=CC2=CN(C3C=CC([C@H]4CNCCC4)=CC=3)N=C12)(=O)N |&1:23,r|

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Niraparib is a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors.

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