Ruxolitinib phosphate
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- ₹0
- Product name: Ruxolitinib phosphate
- CAS: 1092939-17-7
- MF: C17H21N6O4P
- MW: 404.37
- EINECS:
- MDL Number:MFCD18452860
- Synonyms:(betaR)-beta-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile phosphate;INCB 018424;Ruxolitinib, Phosphate Salt;Ruxolitinib, Phosphate;(βR)-β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-1H-pyrazole-1-propanenitrile Phosphate;(3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile phosphoric acid;Ruxolitinib (INCB-18424) phosphate;Jakafi (ruxolitinib)
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Properties
Melting point :186-190°C
storage temp. :Refrigerator
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
color :White to Off-White
InChI :InChI=1/C17H18N6.H3O4P/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16;1-5(2,3)4/h6,8-12,15H,1-5H2,(H,19,20,21);(H3,1,2,3,4)/t15-;/s3
InChIKey :JFMWPOCYMYGEDM-AVAJOTNLNA-N
SMILES :P(O)(O)(O)=O.[C@@H](C1CCCC1)(N1N=CC(C2N=CN=C3NC=CC=23)=C1)CC#N |&1:5,r|
storage temp. :Refrigerator
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
color :White to Off-White
InChI :InChI=1/C17H18N6.H3O4P/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16;1-5(2,3)4/h6,8-12,15H,1-5H2,(H,19,20,21);(H3,1,2,3,4)/t15-;/s3
InChIKey :JFMWPOCYMYGEDM-AVAJOTNLNA-N
SMILES :P(O)(O)(O)=O.[C@@H](C1CCCC1)(N1N=CC(C2N=CN=C3NC=CC=23)=C1)CC#N |&1:5,r|
Safety Information
Symbol(GHS): |
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Signal word: | Danger | ||||||||||||||||||||||||||||
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Description
The phosphate salt of Ruxolitinib (R702000). Ruxolitinib is a selective Janus tyrosine kinase (JAK1 and JAK2) inhibitor used in the treatment of myeloproliferative neoplasms and psoriasis.Related product price
- LIMAPROST
₹19095.3