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ML364

ML364 Structure
  • ₹0
  • Product name: ML364
  • CAS: 1991986-30-1
  • MF: C24H18F3N3O3S2
  • MW: 517.54
  • EINECS:-0
  • MDL Number:MFCD30718174
  • Synonyms:ML364;ML364, 1991986-30-1;ML 364;ML-364;ML364, >98%;Benzamide, 2-[[(4-methylphenyl)sulfonyl]amino]-N-(4-phenyl-2-thiazolyl)-4-(trifluoromethyl)-;ML364 >=98% (HPLC);2-((4-Methylphenyl)sulfonamido)-N-(4-phenylthiazol-2-yl)-4-(trifluoromethyl)benzamide;Deubiquitinase,Inhibitor,ML 364,DUBs,ML-364,ML364,inhibit
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Density :1.457±0.06 g/cm3(Predicted)
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml; Ethanol: 20 mg/ml
form :A crystalline solid
pka :6.51±0.50(Predicted)
color :Light yellow to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

ML364 is a small molecular inhibitor of the deubiquitinase USP2, which accelerates cyclin D1 degrdation and leads to cell cycle arrest in colorectal cancer and mantle cell lymphoma.

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