VU0456810
- ₹11550.28 - ₹46558.33
- Product name: VU0456810
- CAS: 1443246-62-5
- MF: C17H14F2N4O
- MW: 328.32
- EINECS:
- MDL Number:MFCD27977571
- Synonyms:1-(3,4-Difluorophenyl)-3-(3-methyl-1-phenyl-1H-pyrazol-5-yl)urea;CID 56642816;ML297;VU0456810;1-(3,4-DIFLUOROPHENYL)-3-(5-METHYL-2-PHENYLPYRAZOL-3-YL)UREA;ML297, Pubchem: CID 56642816;ML297 (VU0456810);ML 297;ML-297;ML297;VU0456810;VU-0456810;VU 0456810
3 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 10MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML0836
- Product descriptionML297 ≥98% (HPLC)
- Packaging25MG
- Price₹46558.33
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number5.05820
- Product descriptionGIRK Activator, ML297 - CAS 1443246-62-5 - Calbiochem
- Packaging10MG
- Price₹21209.99
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0836
- Product descriptionML297 ≥98% (HPLC)
- Packaging5MG
- Price₹11550.28
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | SML0836 | ML297 ≥98% (HPLC) | 25MG | ₹46558.33 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 5.05820 | GIRK Activator, ML297 - CAS 1443246-62-5 - Calbiochem | 10MG | ₹21209.99 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SML0836 | ML297 ≥98% (HPLC) | 5MG | ₹11550.28 | 2022-06-14 | Buy |
Properties
Boiling point :377.8±42.0 °C(Predicted)
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: soluble15mg/mL, clear
pka :12.54±0.70(Predicted)
form :White powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: soluble15mg/mL, clear
pka :12.54±0.70(Predicted)
form :White powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Safety Information
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Signal word: | Warning | ||||||||||||||
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Description
G protein-regulated inwardly rectifying potassium (GIRK1-4) channels are a family of Kir3.1-Kir3.4 ion channels that modulate cell excitability. The four different GIRK subunits are composed in different homo- and heterotetrameric combinations, which are expressed with regional specificity throughout the central nervous system and in the periphery. ML-297 is a selective GIRK1/2 activator (EC50s = 0.16 and 1.8 μM for GIRK1/2 and GIRK1/4, respectively, and is completely inactive at GIRK2/3). In two different mouse models of epilepsy, ML-297 at 60 mg/kg was shown to delay seizure onset and to prevent convulsions.More related product prices
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