ML-098
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- ₹0
- Product name: ML-098
- CAS: 878978-76-8
- MF: C19H19NO3
- MW: 309.36
- EINECS:
- MDL Number:
- Synonyms:ML-098;ML-809;ML098;ML 098;CS-1456;CID 7345532;CID7345532;CID-7345532;CID-7345532;CID 7345532;CID7345532;ML 098;ML098
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Properties
Boiling point :535.5±45.0 °C(Predicted)
Density :1.17±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:53.0(Max Conc. mg/mL);171.45(Max Conc. mM)
form :A crystalline solid
pka :3.93±0.10(Predicted)
color :White to off-white
Density :1.17±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:53.0(Max Conc. mg/mL);171.45(Max Conc. mM)
form :A crystalline solid
pka :3.93±0.10(Predicted)
color :White to off-white
Safety Information
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Description
The Ras family of GTPases, including the Arf, Rho, Ras, and Rab GTPase subfamilies, regulates various cellular processes ranging from membrane trafficking to the control of cell proliferation. They regulate cell physiology by switching between active and inactive conformational states by binding either GTP or GDP. Alterations in GTPase function are a known hallmark of certain cancers and genetic diseases. ML-098 is an activator of the GTP-binding protein Rab7 (EC50 = 77.6 nM) that demonstrates selectivity against the related GTPases cdc42, Ras, Rab-2A, and Rac1 (EC50s = 588.8, 346.7, 158.5, and 794.3 nM, respectively). It has been shown to function by increasing the affinity of the GTPase for guanine nucleotides.More related product prices
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Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
InvivoChem
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
LEAPCHEM CO., LTD.
Aladdin Scientific
Amadis Chemical Company Limited
Shanghai Weiwei Biological Technology Co., Ltd.
Guangzhou Weijia Technology Co., Ltd.
Shanghai Jingke Chemical Technology Co., Ltd.