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4-Methyl-2-(1-piperidinyl)-quinoline

4-Methyl-2-(1-piperidinyl)-quinoline Structure
  • ₹12394.63 - ₹50076.45
  • Product name: 4-Methyl-2-(1-piperidinyl)-quinoline
  • CAS: 5465-86-1
  • MF: C15H18N2
  • MW: 226.32
  • EINECS:
  • MDL Number:MFCD00817920
  • Synonyms:4-Methyl-2-(1-piperidinyl)-quinoline;ML 204;NSC 25850;ML-204;ML204;4-methyl-2-(piperidin-1-yl)quinoline;Quinoline, 4-methyl-2-(1-piperidinyl)-;Inhibitor,TRP Channel,ML 204,channels,potential,transport,inhibit,membrane,canonical,receptor,ion,ML-204,regulation,Transient receptor potential channels,ML204,transient,biophysics,TRP
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0400
  • Product descriptionML204 ≥98% (HPLC)
  • Packaging5MG
  • Price₹12394.63
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0400
  • Product descriptionML204 ≥98% (HPLC)
  • Packaging25MG
  • Price₹50076.45
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0400 ML204 ≥98% (HPLC) 5MG ₹12394.63 2022-06-14 Buy
Sigma-Aldrich(India) SML0400 ML204 ≥98% (HPLC) 25MG ₹50076.45 2022-06-14 Buy

Properties

Melting point :72-73 °C
Boiling point :177-180 °C(Press: 4.5 Torr)
Density :1.102±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL at warmed (clear solution)
form :powder
pka :7.34±0.61(Predicted)
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

ML-204 selectively blocks transient receptor potential canonical 4 (TRPC4) channels (IC50s = 0.96 and 2.6 μM in fluorescent and electrophysiological assays, respectively). It exhibits 19-fold selectivity against TRPC6 and 9-fold selectivity against TRPC5 and does not affect TRPV1, TRPV3, TRPA1, or TRPM8 channels at concentrations up to 22 μM.

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