Mosapride
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- ₹0
- Product name: Mosapride
- CAS: 112885-41-3
- MF: C21H25ClFN3O3
- MW: 421.89
- EINECS:
- MDL Number:MFCD00867430
- Synonyms:4-AMINO-5-CHLORO-2-ETHOXY-N-[[[4-(4-FLUOROPHENYL)METHYL]-2-MORPHOLINYL]METHYL]-BENZAMIDE;((4-(4-fluorobenzyl)-2-morpholinyl)methyl)benzamide/mosapride;4-Amino-5-Chloro-2-Ethoxy-N-((4-(4-Fluorobenzyl)-2-Morpholinyl)Methyl)Benzamide/Mosapride;MOSAPRIDE;Mosapride/4-Amino-5-Chloro-2-Ethoxy-N-((4-(4-Fluorobenzyl)-2-Morpholinyl)Methyl)Benzamide;Mosapid;Mosid-MT;Moza
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Properties
Melting point :151-153°C
Boiling point :549.2±50.0 °C(Predicted)
Density :1.272±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :13.52±0.46(Predicted)
color :White to Off-White
CAS DataBase Reference :112885-41-3(CAS DataBase Reference)
Boiling point :549.2±50.0 °C(Predicted)
Density :1.272±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :13.52±0.46(Predicted)
color :White to Off-White
CAS DataBase Reference :112885-41-3(CAS DataBase Reference)
Safety Information
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Description
Mosapride citrate, a new gastroprokinetic benzamide was introduced in Japan as Gasmotin for the relief of gastrointestinal symptoms in patients with chronic gastritis, gastro-oesophageal reflux, dyspepsia and post-surgery use. Mosapride is synthesized by final amidation between the corresponding benzoic acid, itself obtained in 3 steps from methyl 4-acetamido salicylate, and the appropriate 2-aminomethyl-morpholine. Mosapride is a 5-HT4 partial agonist without notable activity for D2, 5-HT1 , 5-HT2, alpha-1 and alpha-2 receptors. In dogs, mosapride was as potent as cisapride to stimulate antral and duodenal motility. In most of species including man, mosapride undergoes extensive cleavage to a N-debenzylated metabolite which retains partial 5-HT4 activity but has potent 5-HT3 antagonist activity.Related product price
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₹5000-29898.65
Suppliers and manufacturers
career henan chemical co
A.J Chemicals
CLEARSYNTH LABS LTD.
Pharmaffiliates Analytics and Synthetics P. Ltd
SynZeal Research Pvt Ltd
Chongqing Chemdad Co., Ltd
CONIER CHEM AND PHARMA LIMITED
Career Henan Chemica Co
ANHUI WITOP BIOTECH CO., LTD
Shaanxi Dideu Medichem Co. Ltd
₹1.00 /1KG
4-Amino-5-chloro-2-ethoxy-N-((4-(4-fluorobenzyl)-2-morpholinyl)methyl)benzamide CAS:112885-41-3
4-Amino-5-chloro-2-ethoxy-N-((4-(4-fluorobenzyl)-2-morpholinyl)methyl)benzamide CAS:112885-41-3