Moxifloxacin
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- Product name: Moxifloxacin
- CAS: 151096-09-2
- MF: C21H24FN3O4
- MW: 401.43
- EINECS:604-773-0
- MDL Number:MFCD04117996
- Synonyms:MOXIFLOXACIN;(1'S,6'S)-1-Cyclopropyl-7-(2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihyd;Moxifloxacin EP Impurity;Moxifloxacin Hydrochloride 2;MOXIFLOXACIN HYDROCHELORIDE;MAXIOFFOXACIN;186826-86-8 (Hydrochloride);192927-63-2 (Hydrochloride hydrate)
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Properties
Melting point :203-208 C
alpha :23D -193°
Boiling point :636.4±55.0 °C(Predicted)
Density :1.408±0.06 g/cm3(Predicted)
storage temp. :2-8°C(protect from light)
solubility :Acetonitrile (Slightly), DMSO (Slightly, Heated, Sonicated), Methanol (Slightly)
pka :6.43±0.50(Predicted)
form :Solid
color :Off-White to Light Yellow
Stability :Hygroscopic
CAS DataBase Reference :151096-09-2(CAS DataBase Reference)
EPA Substance Registry System :3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo- (151096-09-2)
alpha :23D -193°
Boiling point :636.4±55.0 °C(Predicted)
Density :1.408±0.06 g/cm3(Predicted)
storage temp. :2-8°C(protect from light)
solubility :Acetonitrile (Slightly), DMSO (Slightly, Heated, Sonicated), Methanol (Slightly)
pka :6.43±0.50(Predicted)
form :Solid
color :Off-White to Light Yellow
Stability :Hygroscopic
CAS DataBase Reference :151096-09-2(CAS DataBase Reference)
EPA Substance Registry System :3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo- (151096-09-2)
Safety Information
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Description
Moxifloxacin is a fourth-generation synthetic fluoroquinolone antibacterial agent developed by Bayer AG (initially called BAY 12-8039), used to treat a number of infections, including: respiratory tract infections, cellulitis, anthrax, intraabdominal infections, endocarditis, meningitis, and tuberculosis. It is marketed worldwide (as the hydrochloride) under the brand names Avelox, Avalox, and Avelon for oral treatment. In most countries, the drug is also available in parenteral form for intravenous infusion.In the United States, moxifloxacin is licensed for the treatment of acute bacterial sinusitis, acute bacterial exacerbation of chronic bronchitis, community acquired pneumonia, complicated and uncomplicated skin and skin structure infections, and complicated intra-abdominal infections.[5] In the European Union, it is licensed for acute bacterial exacerbations of chronic bronchitis, non-severe community-acquired pneumonia, and acute bacterial sinusitis.
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