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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Apoptosis >p53 activator >NSC319726

NSC319726

NSC319726 Structure
  • ₹0
  • Product name: NSC319726
  • CAS: 71555-25-4
  • MF: C11H14N4S
  • MW: 234.32
  • EINECS:
  • MDL Number:MFCD01665446
  • Synonyms:1-Azetidinecarbothioic acid [1-(2-pyridinyl)ethylidene]hydrazide NSC319726;NSC 319726;NSC-319726;(E)-N'-(1-(Pyridin-2-yl)ethylidene)azetidine-1-carbothiohydrazide;1-Azetidinecarbothioic acid [1-(2-pyridinyl)ethylidene]hydrazide;NSC319726;1-Azetidinecarbothioic acid, 2-[1-(2-pyridinyl)ethylidene]hydrazide;Azetidinecarbothioic acid, [1-(2-pyridinyl)ethylidene] hydrazide;CS-981
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :175-176 °C(Solv: acetonitrile (75-05-8))
Boiling point :367.7±34.0 °C(Predicted)
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :insoluble in H2O; ≥3.43 mg/mL in EtOH with gentle warming and ultrasonic; ≥8.1 mg/mL in DMSO
form :solid
pka :11.52±0.20(Predicted)
color :Off-white to light yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

NSC 319726 increases growth inhibitory activity in mutant p53 cells, particularly for the p53R175 mutant. NSC319726 is a p53R175 mutant reactivator and is a lead compound for p53-?targeted drug development.

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