Stattic
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- ₹16259.15 - ₹31190
- Product name: Stattic
- CAS: 19983-44-9
- MF: C8H5NO4S
- MW: 211.19
- EINECS:
- MDL Number:MFCD00173799
- Synonyms:BUTTPARK 97\04-73;6-NITRO-1H-1LAMBDA6-BENZO[B]THIOPHENE-1,1-DIONE;AKOS 1001;6-Nitro-1-benzothiophene 1,1-dioxide;1,1-DIOXO-6-NITROBENZO(B)THIOPHENE;6-Nitrobenzo[b]thiophene-1,1-dioxide, Stat three inhibitory compound;Stattic;6-Nitrobenzo[b]thiophene1,1-dioxide
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberS7947
- Product descriptionStattic ≥98% (HPLC), powder
- Packaging25MG
- Price₹16259.15
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number573099
- Product descriptionSTAT3 Inhibitor V, Stattic - CAS 19983-44-9 - Calbiochem STAT3 Inhibitor V, Stattic, CAS 19983-44-9, is a cell-permeable inhibitor of STAT3 cellular function that targets the STAT3-SH2 domain and prevents it
- Packaging25MG
- Price₹31190
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | S7947 | Stattic ≥98% (HPLC), powder | 25MG | ₹16259.15 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 573099 | STAT3 Inhibitor V, Stattic - CAS 19983-44-9 - Calbiochem STAT3 Inhibitor V, Stattic, CAS 19983-44-9, is a cell-permeable inhibitor of STAT3 cellular function that targets the STAT3-SH2 domain and prevents it | 25MG | ₹31190 | 2022-06-14 | Buy |
Properties
Melting point :187-188 °C
Boiling point :461.1±45.0 °C(Predicted)
Density :1.621±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: >20mg/mL
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Boiling point :461.1±45.0 °C(Predicted)
Density :1.621±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: >20mg/mL
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Safety Information
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Description
Signal transducers and activators of transcription (STATs) are a family of latent cytoplasmic transcription factors that convey signals from the cell membrane to the nucleus. In various human tumors, STAT3 is constitutively activated by aberrant upstream tyrosine kinase activities. Stattic is a small molecule inhibitor of STAT3. It selectively inhibits STAT3 activation, dimerization, and nuclear translocation by preventing the binding of tyrosine-phosphorylated peptide motifs to the STAT3 SH2 domain (IC50 = 5.1 μM at 37°C). At 10 μM, stattic induces apoptosis in STAT3-dependent breast cancer (MDA-MB-231 and MDA-MB-435S) cell lines.More related product prices
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