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ChemicalBook > Product Catalogue >API >Urinary System Drugs >Diabetes insipidus Drugs >Terlipressin acetate

Terlipressin acetate

Terlipressin acetate Structure
  • ₹0
  • Product name: Terlipressin acetate
  • CAS: 14636-12-5
  • MF: C52H74N16O15S2
  • MW: 1227.37
  • EINECS:238-680-8
  • MDL Number:MFCD00155450
  • Synonyms:[N-α-Triglycyl-8-lysine]-vasopressin;130: PN: WO2010033207 SEQID: 171 claiMed protein;1-Triglycyl-8-lysine Vasopressin;Nα-Glycyl-glycyl-glycyl-[8-lysine]-vasopressin;Nα-Glycyl-glycyl-glycyl-lysine-vasopressin;Nα-Glycylglycylglycyl-vasopressin;Nα-Gly-Gly-Gly-8-Lys-vasopressin;Triglycyl-8-lysine-vasopressin
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :>170°C (dec.)
Boiling point :1824.0±65.0 °C(Predicted)
Density :1.46±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :9.90±0.15(Predicted)
color :White
Sequence :Gly-Gly-Gly-c[Cys-Tyr-Phe-Gln-Asn-Cys]-Pro-Lys-Gly-NH2,(Disulfide bridge: Cys-Cys)
InChIKey :BENFXAYNYRLAIU-ITQMCZIINA-N
CAS DataBase Reference :14636-12-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.

Description

Terlipressin acetate is a novel synthetic long-acting vasopressin preparation. It is a kind of prodrug, which is inactive by itself. After the action of aminopeptidase in the body, after removing the three glycyl residues at its N-terminus, it slowly "releases" the active lysine vasopressin. Therefore, terlipressin acts as a reservoir that releases lysine vasopressin at a steady rate.

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