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X-376

X-376 Structure
  • ₹0
  • Product name: X-376
  • CAS: 1365267-27-1
  • MF: C25H25Cl2FN6O3
  • MW: 547.41
  • EINECS:
  • MDL Number:MFCD25976868
  • Synonyms:X-376;X-396;6-Amino-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-N-[4-[(4-methyl-1-piperazinyl)carbonyl]phenyl]-3-pyridazinecarboxamide;Ensartinib;(R)-6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-N-(4-(4-methylpiperazine-1-carbonyl)phenyl)pyridazine-3-carboxamide;6-amino-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-N-[4-(4-methylpiperazine-1-carbonyl)phenyl]pyridazine-3-carboxamide;CS-1720;3-Pyridazinecarboxamide, 6-amino-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-N-[4-[(4-methyl-1-piperazinyl)carbonyl]phenyl]-
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Boiling point :695.1±55.0 °C(Predicted)
Density :1.428±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Ethanol:13.0(Max Conc. mg/mL);23.75(Max Conc. mM)
form :A crystalline solid
pka :10.70±0.70(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

X-376 is an ALK inhibitor with potential efficacy in the treatment of non-small cell lung cancer.

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