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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >protein tyrosine kinase >Momelotinib

Momelotinib

Momelotinib Structure
  • ₹0
  • Product name: Momelotinib
  • CAS: 1056634-68-4
  • MF: C23H22N6O2
  • MW: 414.46
  • EINECS:
  • MDL Number:MFCD16038899
  • Synonyms:CYT387, >=98%;CYT 11387;CYT 387;N-(Cyanomethyl)-4-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]benzamide;LM-1149;CYT 387(CYT 11387);N-(cyanoMethyl)-4-(2-(4-Morpholin-4-ylphenylaMino)pyriMidin-4-yl)benzaMide;MoMelotinib
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Density :1.292
storage temp. :Store at -20°C
solubility :insoluble in EtOH; insoluble in H2O; ≥20.7 mg/mL in DMSO
pka :10.94±0.46(Predicted)
form :Orange powder.
color :Light yellow to yellow
CAS DataBase Reference :1056634-68-4

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Momelotinib (CYT387) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, ~10-fold selectivity versus JAK3. Phase 3.

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