AKTI-1/2
![]() |
- ₹20250 - ₹24590.01
- Product name: AKTI-1/2
- CAS: 612847-09-3
- MF: C34H29N7O
- MW: 551.64
- EINECS:1592732-453-0
- MDL Number:MFCD09026909
- Synonyms:1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]guinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-on;1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-γ],guinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-one;1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]guinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-one;1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-2H-benzimidazol-2-one;2H-BenziMidazol-2-one, 1,3-dihydro-1-[1-[[4-(6-phenyl-1H-iMidazo[4,5-g]quinoxalin-7-yl)phenyl]Methyl]-4-piperidinyl]-;AKT inhibitor VIII (AKTI-1/2);1-(1-(4-(6-Phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)benzyl)-piperidin-4-yl)-1H-benzo[d]imidazol-2(;1-(1-(4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)benzyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
3 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 1MG
- 5MG
- 100MG
- ManufacturerTCI Chemicals (India)
- Product numberA3153
- Product descriptionAKT Inhibitor VIII
- Packaging100MG
- Price₹23000
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number124018
- Product descriptionAkt Inhibitor VIII, Isozyme-Selective, Akti-1/2 - CAS 612847-09-3 - Calbiochem Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2, CAS 612847-09-3, is a cell-permeable, reversible inhibitor of Akt1/Akt2 (IC?? = 58 nM, 210 nM, & 2.12
- Packaging1MG
- Price₹20250
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number124018
- Product descriptionAkt Inhibitor VIII, Isozyme-Selective, Akti-1/2 - CAS 612847-09-3 - Calbiochem Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2, CAS 612847-09-3, is a cell-permeable, reversible inhibitor of Akt1/Akt2 (IC?? = 58 nM, 210 nM, & 2.12
- Packaging5MG
- Price₹24590.01
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | A3153 | AKT Inhibitor VIII | 100MG | ₹23000 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | 124018 | Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 - CAS 612847-09-3 - Calbiochem Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2, CAS 612847-09-3, is a cell-permeable, reversible inhibitor of Akt1/Akt2 (IC?? = 58 nM, 210 nM, & 2.12 | 1MG | ₹20250 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 124018 | Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 - CAS 612847-09-3 - Calbiochem Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2, CAS 612847-09-3, is a cell-permeable, reversible inhibitor of Akt1/Akt2 (IC?? = 58 nM, 210 nM, & 2.12 | 5MG | ₹24590.01 | 2022-06-14 | Buy |
Properties
Melting point :242-245°C (dec.)
Density :1.350±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :insoluble in H2O; insoluble in EtOH; ≥9.2 mg/mL in DMSO
pka :7.49±0.50(Predicted)
form :Yellow solid
color :White to Yellow to Orange
CAS DataBase Reference :612847-09-3
Density :1.350±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :insoluble in H2O; insoluble in EtOH; ≥9.2 mg/mL in DMSO
pka :7.49±0.50(Predicted)
form :Yellow solid
color :White to Yellow to Orange
CAS DataBase Reference :612847-09-3
Safety Information
Symbol(GHS): |
![]() |
|||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal word: | Warning | |||||||||||||||||||||||||||||||||||
Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
Precautionary statements: |
|
Description
Three related forms of the kinase Akt (1, 2, 3, also known as protein kinase B isoforms PKBα, β, γ) modulate cell proliferation, metabolism, and survival as well as angiogenesis. Akt inhibitor VIII is a potent allosteric inhibitor of Akt1 and Akt2 (IC50s = 58 and 210 nM, respectively) that less effectively blocks Akt3 activity (IC50 = 2.2 μM). It is a poor or ineffective inhibitor of a wide range of other serine-threonine kinases. Akt inhibitor VIII is cell permeable, blocking insulin regulation of forkhead box 01 activity at 1 μM in rat hepatoma cells.More related product prices
918504-65-1 Dacomitinib (PF299804) Cabozantinib HYDROXY PENTOXIFYLLINE N-[2-Chloro-4-[(6,7-dimethoxy-4-quinolyl)oxy]phenyl]-N'-(5-methyl-3-isoxazolyl)urea BKM120 (NVP-BKM120, Buparlisib) Binimetinib Xylene 4'-Hydroxyacetophenone N,N'-Diphenylurea TPP Aminodiphenylmethane (5-METHYL-1H-PYRAZOL-3-YL)-(2-PHENYLQUINAZOLIN-4-YL)AMINERelated product price
- Dacomitinib (PF299804)
₹5000-14200 - Xylene
₹360-39065.55 - 4'-Hydroxyacetophenone
₹520-45378.4