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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Angina Pectoris Drugs >Amlodipine Besylate

Amlodipine Besylate

Amlodipine Besylate Structure
  • ₹5300 - ₹62319.53
  • Product name: Amlodipine Besylate
  • CAS: 111470-99-6
  • MF: C26H31ClN2O8S
  • MW: 567.05094
  • EINECS:1312995-182-4
  • MDL Number:MFCD00887594
  • Synonyms:Vazkor;3-Ethyl 5-Methyl 2-(2-Aminoethoxy)methyl-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate Benzenesulfonate 2-(2-Aminoethoxy)methyl-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic Acid 3-Ethyl 5-Methyl Ester Benzenesulfona;3-ethyl 5-Methyl 2-((2-aMinoethoxy)Methyl)-4-(2-chlorophenyl)-6-Methyl-1,4-dihydropyridine-3,5-dicarboxylate benzenesulfonate;2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid-3-ethyl 5-methyl ester, benzenesulfonate (1:1);Amlodipine besylate Amlodipine besilate;2-(2-Aminoethoxy)methyl-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic Acid 3-Ethyl 5-Methyl Ester Benzenesulfonate;3-Ethyl 5-Methyl 2-(2-Aminoethoxy)methyl-4-(2-chlorophenyl)-6-methyl-1,4-dihydro;2-[(2-AMINOETHOXY)-METHYL]-4-(2-CHLOROPHENYL)-1,4-DIHYDRO-6-METHYL-3,5-PYRIDINEDICARBOXYLIC ACID 3-ETHYL 5-METHYL ESTER BENZENE SULFONATE
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberA2353
  • Product descriptionAmlodipine Besylate
  • Packaging1G
  • Price₹5300
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberA2353
  • Product descriptionAmlodipine Besylate
  • Packaging5G
  • Price₹10700
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1185
  • Product descriptionAmlodipine besylate Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹8443.5
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA5605
  • Product descriptionAmlodipine besylate ≥98% (HPLC)
  • Packaging10MG
  • Price₹15349.85
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA5605
  • Product descriptionAmlodipine besylate ≥98% (HPLC)
  • Packaging50MG
  • Price₹62319.53
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) A2353 Amlodipine Besylate 1G ₹5300 2022-05-26 Buy
TCI Chemicals (India) A2353 Amlodipine Besylate 5G ₹10700 2022-05-26 Buy
Sigma-Aldrich(India) PHR1185 Amlodipine besylate Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹8443.5 2022-06-14 Buy
Sigma-Aldrich(India) A5605 Amlodipine besylate ≥98% (HPLC) 10MG ₹15349.85 2022-06-14 Buy
Sigma-Aldrich(India) A5605 Amlodipine besylate ≥98% (HPLC) 50MG ₹62319.53 2022-06-14 Buy

Properties

Melting point :199-201°C
storage temp. :2-8°C
solubility :DMSO: 20 mg/mL
form :solid
pka :8.6
color :white
Water Solubility :Soluble in DMSO (20 mg/mL), water (10 mM), chloroform, ethanol (14 mg/mL), and methanol.
Merck :14,491
BCS Class :1 (CLogP) 3 (LogP)
InChIKey :ZPBWCRDSRKPIDG-UHFFFAOYSA-N
CAS DataBase Reference :111470-99-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501 Dispose of contents/container to..…

Description

Amlodipine (generic name Amlodipine Besylate) is a class of calcium channel blockers. One of the amlodipine product on the market is Norvasc®.
Amlodipine functionalizes by the dilation of blood vessels and the improvement of blood flow, which lead to lowered blood pressure. Thereby, it is used to treat high bold pressure (hypertension). Lowering high blood pressure also reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions, and kidney problems. Amlodipine is also used to prevent certain types of chest pains (angina), which may help to increase the ability to exercise and decrease the frequency of angina attacks. Amlodipine can be used to treat coronary artery disease (CAD) including chronic stable angina, vasospastic angina, and angiographically documented CAD.

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