ChemicalBook > Product Catalog >API >Circulatory system drugs >Angina Pectoris Drugs >Amlodipine Besylate
Amlodipine Besylate
- CAS No.
- 111470-99-6
- Chemical Name:
- Amlodipine Besylate
- Synonyms
- AMLODIPINE BESILATE;NORVASC;Amlor;Calchek;AMlodipine bes;Amlodipine besilate (crystalline);Vazkor;Amcard;Lowrac;Norvas
- CBNumber:
- CB4127875
- Molecular Formula:
- C26H31ClN2O8S
- Molecular Weight:
- 567.05094
- MOL File:
- 111470-99-6.mol
- Modify Date:
- 2024/7/3 16:00:59
| Melting point | 199-201°C |
|---|---|
| storage temp. | 2-8°C |
| solubility | DMSO: 20 mg/mL |
| form | solid |
| pka | 8.6 |
| color | white |
| Water Solubility | Soluble in DMSO (20 mg/mL), water (10 mM), chloroform, ethanol (14 mg/mL), and methanol. |
| Merck | 14,491 |
| BCS Class | 1 (CLogP) 3 (LogP) |
| InChIKey | ZPBWCRDSRKPIDG-UHFFFAOYSA-N |
| CAS DataBase Reference | 111470-99-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P501 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | US7967700 | |||||||||
| HS Code | 29333990 | |||||||||
| NFPA 704 |
|
Amlodipine Besylate price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | PHR1185 | Amlodipine besylate Pharmaceutical Secondary Standard; Certified Reference Material | 111470-99-6 | 1G | ₹8443.5 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A5605 | Amlodipine besylate ≥98% (HPLC) | 111470-99-6 | 10MG | ₹15349.85 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A5605 | Amlodipine besylate ≥98% (HPLC) | 111470-99-6 | 50MG | ₹62319.53 | 2022-06-14 | Buy |
| TCI Chemicals (India) | A2353 | Amlodipine Besylate | 111470-99-6 | 1G | ₹5300 | 2022-05-26 | Buy |
| TCI Chemicals (India) | A2353 | Amlodipine Besylate | 111470-99-6 | 5G | ₹10700 | 2022-05-26 | Buy |
Amlodipine Besylate Chemical Properties,Uses,Production
Description
Anilodipine besylate is a new, once-daily, dihydropyridine calcium antagonist useful in the treatment of hypertension and angina.
Chemical Properties
White Crystalline Solid
Uses
Amlodipine besylate is a L-type calcium channel blocker which may be used for the treatment of angina pectoris and hypertension. Amlodipine also inhibits growth of human epidermoid carcinoma A431 cells and has antireproductive effects in male rats.
Definition
ChEBI: The benzenesulfonate salt of amlodipine.
General Description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Amlodipine besylate is a calcium channel blocker, which inhibits the trans membrane influx of calcium ions into vascular smooth muscles and cardiac muscle. It belongs to the dihydropyridine family. It is used in combination with atorvastatin calcium to treat vasospastic angina, chronic stable angina, hypertension, in elevated serum triglyceride levels, primary dysbetalipoproteinemia.
Biological Activity
L-type calcium channel blocker that displays antihypertensive properties. Inhibits Ca 2+ -induced contractions in depolarized rat aorta (IC 50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease. Inhibits proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells (IC 50 = 25 μ M).
Amlodipine Besylate Preparation Products And Raw materials
Raw materials
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Global( 895)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Cadila Pharmaceuticals Ltd | +91-7069076657 +91-7069076657 | Ahmedabad, India | 54 | 58 | Inquiry |
| Micro Orgo Chem | +91-91-022-24969510 +91-9082984052 | Mumbai, India | 66 | 58 | Inquiry |
| Dr. Reddy's Laboratories Ltd | +91-4049002900 +91-4049002900 | Hyderabad, India | 165 | 58 | Inquiry |
| Anant Pharmaceuticals Pvt Ltd | +91-8550986868 +91-9485998001 | Haryana, India | 461 | 58 | Inquiry |
| SURYA LIFE SCIENCES LIMITED | +91-2646226290 +91-9428511112 | Gujarat, India | 62 | 58 | Inquiry |
| PRODIGIOUS LIFE SCIENCES | +91-9177472555 +91-9177472555 | Hyderabad, India | 236 | 58 | Inquiry |
| Frolic Pharmachem | +919711094561 | Himachal Pradesh, India | 94 | 58 | Inquiry |
| AARTIA KEM SCIENCE | +91-8291072530 +91-8291072530 | Maharashtra, India | 70 | 58 | Inquiry |
| Gonane Pharma | +91-9819380043 +91-9819380043 | NaviMumbai, India | 192 | 58 | Inquiry |
| Cefa-Cilinas Biotics Pvt Ltd | +91-7875033155 +91-8080701561 | Maharashtra, India | 121 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Cadila Pharmaceuticals Ltd | 58 |
| Micro Orgo Chem | 58 |
| Dr. Reddy's Laboratories Ltd | 58 |
| Anant Pharmaceuticals Pvt Ltd | 58 |
| SURYA LIFE SCIENCES LIMITED | 58 |
| PRODIGIOUS LIFE SCIENCES | 58 |
| Frolic Pharmachem | 58 |
| AARTIA KEM SCIENCE | 58 |
| Gonane Pharma | 58 |
| Cefa-Cilinas Biotics Pvt Ltd | 58 |
111470-99-6(Amlodipine Besylate)Related Search:
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Vazkor
3-Ethyl 5-Methyl 2-(2-Aminoethoxy)methyl-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate Benzenesulfonate
2-(2-Aminoethoxy)methyl-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic Acid 3-Ethyl 5-Methyl Ester Benzenesulfona
3-ethyl 5-Methyl 2-((2-aMinoethoxy)Methyl)-4-(2-chlorophenyl)-6-Methyl-1,4-dihydropyridine-3,5-dicarboxylate benzenesulfonate
2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid-3-ethyl 5-methyl ester, benzenesulfonate (1:1)
Amlodipine besylate
Amlodipine besilate
2-(2-Aminoethoxy)methyl-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic Acid 3-Ethyl 5-Methyl Ester Benzenesulfonate
3-Ethyl 5-Methyl 2-(2-Aminoethoxy)methyl-4-(2-chlorophenyl)-6-methyl-1,4-dihydro
2-[(2-AMINOETHOXY)-METHYL]-4-(2-CHLOROPHENYL)-1,4-DIHYDRO-6-METHYL-3,5-PYRIDINEDICARBOXYLIC ACID 3-ETHYL 5-METHYL ESTER BENZENE SULFONATE
2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine benzenesulfonate
Amlodipine Besylate (350 mg)
Ethyl 2-[(2-aminoethoxy)methyl]-4-(2-chloropohenyl)-1,4-dihydro-5-(methoxycarbonyl)-6-methylpyridine-3-carboxylate benzenesulphonate
2-(2-Aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid 3-ethyl=5-methyl·benzenesulfonic acid
C20H25ClN2O5C6H5SO3H
AMLODIPINE BENZENESULFONATE
AMLODIPINE BESYLATE
3,5-pyridinedicarboxylicacid,2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,
4-dihydro-6-methyl-,3-ethyl-5-methylester,monobenzenesulfonate
AMLODIPINE BESILATE MM(CRM STANDARD)
AMLODIPINE BESYLATE EPY(CRM STANDARD)
AMLODIPINEBESYLATE(SUBJECTTOPATENTFREE)
(+-)-3-Ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate monobenzenesulfonate
3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, monobenzenesulfonate
Amcard
Amdepin
Amdipin
Amlodin
Amlopin
Amlosyn
Antacal
Benzenesulfonic acid, compd. with 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate (1:1)
Lowrac
Monopina
Norvas
Norvask
Tensivask
UK 48340-26
2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester benzenesulfonate
raw material amlodipine besylate
Amlodipine Beaylate
Amlodipine benzene sulfonic acid amlodipine
Amlodipine besilate 111470-99-6
2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid O3-ethyl ester O5-methyl ester
Amlodipine Besilate RS
Amlodipine Besylate >
Amlodipine besilate CRS
Amlodipine for peak identification CRS
Amlodipine Besylte
Amlodipine besilate Solution,100μg/mL
2-(2-Aminoethoxy)methyl-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic Acid 3-Ethyl 5-Methyl Ester Benzenesulfona
Amlodipine Besylate USP/EP/BP
AmlodipineBesilatehcl88150-42-9 USP/EP/BP
Amlodipine BesylateQ: What is
Amlodipine Besylate Q: What is the CAS Number of
Amlodipine Besylate Q: What is the storage condition of
Amlodipine Besylate Q: What are the applications of
Amlodipine Besylate
Amlodipine besilate (Y0000049)
Amlodipine For Peak IdentificationQ: What is
Amlodipine For Peak Identification Q: What is the CAS Number of
Amlodipine For Peak Identification
Amlodipine for peak identification (Y0001067)
Amlodipine Besylate (1029501)
AMLODIPINE BESILATE
NORVASC