Bivalirudin
|
- ₹10078.08 - ₹40269
- Product name: Bivalirudin
- CAS: 128270-60-0
- MF: C98H138N24O33
- MW: 2180.29
- EINECS:274-570-6
- MDL Number:MFCD08282793
- Synonyms:Bivalirudin, TFA;BIVALIRUDIN;BITTERMELONP.E;Human Bivalirudin;DPHE-PRO-ARG-PRO-GLY-GLY-GLY-GLY-ASN-GLY-ASP-PHE-GLU-GLU-LLE-PRO-GLU-GLU-TYR-LEU;Bivalirudin BG 8967, Hirulog, Hirulog I;BG 8967, Hirulog, Hirulog I;H-D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 10MG
- 50MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML1051
- Product descriptionBivalirudin trifluoroacetate salt ≥97% (HPLC)
- Packaging50MG
- Price₹40269
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML1051
- Product descriptionBivalirudin trifluoroacetate salt ≥97% (HPLC)
- Packaging10MG
- Price₹10078.08
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML1051 | Bivalirudin trifluoroacetate salt ≥97% (HPLC) | 50MG | ₹40269 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML1051 | Bivalirudin trifluoroacetate salt ≥97% (HPLC) | 10MG | ₹10078.08 | 2022-06-14 | Buy |
Properties
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :≥54.5 mg/mL in DMSO with gentle warming; ≥10.18 mg/mL in EtOH with gentle warming and ultrasonic; ≥43.5 mg/mL in H2O with gentle warming
form :powder
color :white to off-white
Sequence :D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH
InChIKey :OIRCOABEOLEUMC-GEJPAHFPSA-N
storage temp. :-20°C
solubility :≥54.5 mg/mL in DMSO with gentle warming; ≥10.18 mg/mL in EtOH with gentle warming and ultrasonic; ≥43.5 mg/mL in H2O with gentle warming
form :powder
color :white to off-white
Sequence :D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH
InChIKey :OIRCOABEOLEUMC-GEJPAHFPSA-N
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
Bivalirudin is an inhibitor of α- and ζ-thrombin (Kis = 2.56 and 1.84 nM, respectively), enzymes that exhibit high fibrinogen-clotting activities. It is selective for α- and ζ-thrombin, lacking activity at trypsin and γ-thrombin, which lacks clotting activity, at a >1,000-fold excess of bivalirudin. Bivalirudin inhibits α-thrombin-stimulated activation of the clotting factors Factor X, Factor V, and prothrombin in contact-activated plasma at a concentration of 0.1 μM. Administration of bivalirudin (0.5-1.5 mg/kg, i.v.) reduces platelet deposition in a rat carotid endarterectomy model in a dose-dependent manner. Formulations containing bivalirudin have been used to prevent ischemic events during angioplasty for thrombus-containing lesions.Related product price
- Oxytocin
₹4959 - 15-28-Somatostatin-28
₹5109.4-77117.3 - Octreotide acetate
₹28318.2-41232.43