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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Angina Pectoris Drugs >Buflomedil hydrochloride

Buflomedil hydrochloride

Buflomedil hydrochloride Structure
  • ₹2300 - ₹7600
  • Product name: Buflomedil hydrochloride
  • CAS: 35543-24-9
  • MF: C17H26ClNO4
  • MW: 343.85
  • EINECS:252-611-9
  • MDL Number:MFCD00078965
  • Synonyms:BUFLOMEDIL HCL EP;BuflomedilHclC17H25No4.Hcl;BUFLOMEDIL HYDROCHLORIDE;ll1656 ;2',4',6-Trimethoxy-4-[1-pyrrolidinyl] butyrophenone hydrochloride;Buflan;Durabuflo;Buflocit
3 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberB3647
  • Product descriptionBuflomedil Hydrochloride
  • Packaging1G
  • Price₹2300
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberB3647
  • Product descriptionBuflomedil Hydrochloride
  • Packaging5G
  • Price₹7600
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberB5899
  • Product descriptionBuflomedil hydrochloride analytical standard
  • Packaging1G
  • Price₹3323.28
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) B3647 Buflomedil Hydrochloride 1G ₹2300 2022-05-26 Buy
TCI Chemicals (India) B3647 Buflomedil Hydrochloride 5G ₹7600 2022-05-26 Buy
Sigma-Aldrich(India) B5899 Buflomedil hydrochloride analytical standard 1G ₹3323.28 2022-06-14 Buy

Properties

Melting point :192-193°
storage temp. :Inert atmosphere,Room Temperature
solubility :Freely soluble in water, soluble in ethanol (96 per cent), very slightly soluble in acetone.
form :Solid
color :White to Off-White
InChIKey :ZDPACSAHMZADFZ-UHFFFAOYSA-N
CAS DataBase Reference :35543-24-9(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P501 Dispose of contents/container to..…

Description

Buflomedil hydrochloride is a vasoactive drug with a variety of actions. It is an alpha-adrenoceptor antagonist and a weak calcium channel blocker. It inhibits platelet aggregation and improves erythrocyte deformability. However, its mechanism of action in peripheral vascular disease is not known.
Buflomedil has generally been well tolerated by most patients in clinical trials. The most frequently reported adverse effects include flushing, headache, vertigo, gas-trointestinal discomfort, and dizziness. These rarely require drug withdrawal. In controlled trials, adverse effects have occurred in 20% of patients assigned to buflomedil and 18% of those assigned to placebo; only gastrointestinal discomfort occurred more frequently in buflomedil-treated patients (3.4 versus 2%)

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