Eplerenone
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- ₹8800 - ₹81772.05
- Product name: Eplerenone
- CAS: 107724-20-9
- MF: C24H30O6
- MW: 414.49
- EINECS:600-850-8
- MDL Number:MFCD05662207
- Synonyms:(2'R,4aS,4bR,5aR,6aS,9aS,9bR,10R)-Methyl 4a,6a-diMethyl-2,4'-dioxo-3,4,4a,4',5a,5',6,6a,8,9,9a,9b,10,11-tetradecahydro-2H,3'H-spiro[cyclopenta[1,2]phenanthro[4,4a-b]oxirene-7,2'-furan]-10-carboxylate;HSDB 7522;Pregn-4-ene-7,21-dicarboxylic acid, 9,11-epoxy-17-hydroxy-3-oxo-, gamma-lactone, methyl ester, (7alpha,11alpha,17alpha)-;Eplerenone intermediate Eplerenone;(7α,11α,17α)-9,11-epoxy-17-hydroxy-3-oxo-γ-lactone-pregn-4-ene-7,21-dicarboxylic acid-7-methyl ester;Eplerenone for system suitability;Eplerenone for peak identification;EPLERENONE
3 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 10MG
- 50MG
- 200MG
- ManufacturerTCI Chemicals (India)
- Product numberE0905
- Product descriptionEplerenone
- Packaging200MG
- Price₹8800
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberE6657
- Product descriptionEplerenone ≥98% (HPLC)
- Packaging10MG
- Price₹21152.05
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberE6657
- Product descriptionEplerenone ≥98% (HPLC)
- Packaging50MG
- Price₹81772.05
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | E0905 | Eplerenone | 200MG | ₹8800 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | E6657 | Eplerenone ≥98% (HPLC) | 10MG | ₹21152.05 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | E6657 | Eplerenone ≥98% (HPLC) | 50MG | ₹81772.05 | 2022-06-14 | Buy |
Properties
Melting point :241-243°C
alpha :D +5° (c = 0.437 in chloroform)
Boiling point :597.9±50.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :Store at RT
solubility :DMSO: soluble2mg/mL, clear (warmed)
form :powder
color :white to beige
λmax :240nm(lit.)
Merck :14,3625
InChIKey :UZZAHAKTLYRDOK-MGIDJNSKSA-N
SMILES :[C@@]123[C@@]4(C)CCC(=O)C=C4C[C@@H](C(OC)=O)[C@@]1([H])[C@]1([H])CC[C@]4(CCC(=O)O4)[C@]1(C[C@@]2([H])O3)C |&1:0,1,10,15,17,21,27,29,r|
alpha :D +5° (c = 0.437 in chloroform)
Boiling point :597.9±50.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :Store at RT
solubility :DMSO: soluble2mg/mL, clear (warmed)
form :powder
color :white to beige
λmax :240nm(lit.)
Merck :14,3625
InChIKey :UZZAHAKTLYRDOK-MGIDJNSKSA-N
SMILES :[C@@]123[C@@]4(C)CCC(=O)C=C4C[C@@H](C(OC)=O)[C@@]1([H])[C@]1([H])CC[C@]4(CCC(=O)O4)[C@]1(C[C@@]2([H])O3)C |&1:0,1,10,15,17,21,27,29,r|
Safety Information
Symbol(GHS): |
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Signal word: | Warning | ||||||||||||||||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
Eplerenone is a potassium-sparing diuretic that selectively blocks aldosterone activation of the mineralcorticoid receptor (IC50 = 122 nM), demonstrating little activity towards other steroid receptors (IC50 > 9 μM for glucocorticoid, androgen, progesterone, and estrogen receptors). Aldosterone antagonists such as this compound have been indicated for the treatment of hypertension and heart failure.Related product price
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