JNJ-10198409
- ₹19050 - ₹78719.4
- Product name: JNJ-10198409
- CAS: 627518-40-5
- MF: C18H16FN3O2
- MW: 325.34
- EINECS:
- MDL Number:MFCD11045292
- Synonyms:PDGFR Tyrosine Kinase Inhibitor IV;JNJ-10198409;Indeno[1,2-c]pyrazol-3-amine, N-(3-fluorophenyl)-1,4-dihydro-6,7-dimethoxy-;RWJ 540973, 3-Fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamine, N-(3-fluorophenyl)-2,4-dihydro-6,7-dimethoxy-Indeno[1,2-c]pyrazol-3-amine;JNJ-10198409, Free Base;3-Fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamine;N-(3-fluorophenyl)-2,4-dihydro-6,7-dimethoxy-Indeno[1,2-c]pyrazol-3-amine;RWJ 540973
3 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 1MG
- 5MG
- ManufacturerSigma-Aldrich(India)
- Product number521233
- Product descriptionPDGFR Tyrosine Kinase Inhibitor IV - CAS 627518-40-5 - Calbiochem
- Packaging1MG
- Price₹19050
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberJ4649
- Product descriptionJNJ-10198409 ≥98% (HPLC), solid
- Packaging1MG
- Price₹19658.2
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberJ4649
- Product descriptionJNJ-10198409 ≥98% (HPLC), solid
- Packaging5MG
- Price₹78719.4
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 521233 | PDGFR Tyrosine Kinase Inhibitor IV - CAS 627518-40-5 - Calbiochem | 1MG | ₹19050 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | J4649 | JNJ-10198409 ≥98% (HPLC), solid | 1MG | ₹19658.2 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | J4649 | JNJ-10198409 ≥98% (HPLC), solid | 5MG | ₹78719.4 | 2022-06-14 | Buy |
Properties
Melting point :171-173.5 °C
Boiling point :528.8±50.0 °C(Predicted)
Density :1.366±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMSO: >10mg/mL
form :solid
pka :14.01±0.20(Predicted)
color :off-white
Boiling point :528.8±50.0 °C(Predicted)
Density :1.366±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMSO: >10mg/mL
form :solid
pka :14.01±0.20(Predicted)
color :off-white
Safety Information
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Description
PDGFR Tyrosine Kinase Inhibitor IV is a indenopyrazole compound that displays potent antiproliferative properties in human tumor cell lines. It acts as a reversible ATP-competitive inhibitor of PDGFR but exhibits less actibity towards Lck, c-Src, and Fyn while exhibiting little to no inhibition toward VEGFR, HER-2, Cdk's-1,-2,-4 &-7, bFGFR-1 and EGFR. PDGFR Tyrosine Kinase Inhibitor IV is cell-permeable. PDGFR Tyrosine Kinase Inhibitor IV is an inhibitor of c-Abl, PDGFR-α and PDGFR-β.More related product prices
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