Loperamide hydrochloride
- ₹5564.05 - ₹58065.3
- Product name: Loperamide hydrochloride
- CAS: 34552-83-5
- MF: C29H34Cl2N2O2
- MW: 513.5
- EINECS:252-082-4
- MDL Number:MFCD00058581
- Synonyms:4-(4-(p-chlorophenyl)-4-hydroxy-1-piperidyl)-n,n-dimethyl-2,2-diphenylbutyra ;4-(p-chlorophenyl)-4-hydroxy-n,n-dimethyl-alpha,alpha-diphenyl-1-piperidine ;blox ;butyramidehcl ;dissenten ;fortasec ;imodium ;imosec
7 prices
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Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 100MG
- 1G
- 5G
- 25G
- ManufacturerTCI Chemicals (India)
- Product numberL0154
- Product descriptionLoperamide Hydrochloride
- Packaging5G
- Price₹9800
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberL0154
- Product descriptionLoperamide Hydrochloride
- Packaging25G
- Price₹16000
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number34014
- Product descriptionLoperamide hydrochloride VETRANAL?, analytical standard
- Packaging100MG
- Price₹5564.05
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPHR1162
- Product descriptionLoperamide hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging1G
- Price₹9753.33
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number5.08162
- Product descriptionLoperamide Hydrochloride - CAS 34552-83-5 - Calbiochem
- Packaging1G
- Price₹10550.01
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberL4762
- Product descriptionLoperamide hydrochloride
- Packaging5G
- Price₹14570.45
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberL4762
- Product descriptionLoperamide hydrochloride
- Packaging25G
- Price₹58065.3
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | L0154 | Loperamide Hydrochloride | 5G | ₹9800 | 2022-05-26 | Buy |
TCI Chemicals (India) | L0154 | Loperamide Hydrochloride | 25G | ₹16000 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | 34014 | Loperamide hydrochloride VETRANAL?, analytical standard | 100MG | ₹5564.05 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR1162 | Loperamide hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material | 1G | ₹9753.33 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 5.08162 | Loperamide Hydrochloride - CAS 34552-83-5 - Calbiochem | 1G | ₹10550.01 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | L4762 | Loperamide hydrochloride | 5G | ₹14570.45 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | L4762 | Loperamide hydrochloride | 25G | ₹58065.3 | 2022-06-14 | Buy |
Properties
Melting point :223-225°C
Density :1.1905 (rough estimate)
refractive index :1.6100 (estimate)
storage temp. :2-8°C
solubility :Slightly soluble in water, freely soluble in ethanol (96 per cent) and in methanol.
pka :8.66(at 25℃)
form :Solid
color :White to Almost white
Merck :14,5571
CAS DataBase Reference :34552-83-5(CAS DataBase Reference)
Density :1.1905 (rough estimate)
refractive index :1.6100 (estimate)
storage temp. :2-8°C
solubility :Slightly soluble in water, freely soluble in ethanol (96 per cent) and in methanol.
pka :8.66(at 25℃)
form :Solid
color :White to Almost white
Merck :14,5571
CAS DataBase Reference :34552-83-5(CAS DataBase Reference)
Safety Information
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Signal word: | Danger | ||||||||||||||
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Description
Loperamide is an opiate which potently and selectively activates μ opioid receptors (Ki = 0.16 nM) exclusively in the periphery. Loperamide is an opiate which potently and selectively activates μ opioid receptors (Ki = 0.16 nM) exclusively in the periphery. It is a much weaker agonist of the δ opiod receptor (Ki = 50 nM). Through its actions in the gut wall, loperamide has antidiarrheal action by increasing transit time and by altering intestinal transport of water and electrolytes. It also blocks voltage-sensitive sodium channels (IC50 = 270 nM) and high voltage-activated calcium channels (IC50 = 900 nM), presumably through an inhibitory effect on calmodulin. Loperamide is comparable to morphine in blocking peripheral pain in rats.More related product prices
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