Oridonin
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- ₹10670 - ₹55737.93
- Product name: Oridonin
- CAS: 28957-04-2
- MF: C20H28O6
- MW: 364.44
- EINECS:
- MDL Number:MFCD00221762
- Synonyms:Oridonin, R. rubescens;ISODONAL;(14r)-7-alpha,20-epoxy-1-alpha,6-beta,7,14-tetrahydroxykaur-16-en-15-one ;(1-alpha,6-beta,7-alpha,14r)-7,20-epoxy-1,6,7,14-tetrahydroxykaur-16-en-15-o ;,14r)- ;20-epoxy-1-alpha,6-beta,7,14-tetrahydroxy-7-alph(14r)-kaur-16-en-15-on ;kaur-16-en-15-one,7,20-epoxy-1,6,7,14-tetrahydroxy-,(1-alpha,6-beta,7-alpha ;Rubescensin
3 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product number496915
- Product descriptionOridonin, R. rubescens - CAS 28957-04-2 - Calbiochem A cell-permeable diterpenoid compound that possesses anti NF-κB activity and displays antiproliferative and antiangiogenic properties.
- Packaging5MG
- Price₹10670
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberO9639
- Product descriptionOridonin ≥98% (HPLC), solid
- Packaging5MG
- Price₹13964.25
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberO9639
- Product descriptionOridonin ≥98% (HPLC), solid
- Packaging25MG
- Price₹55737.93
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 496915 | Oridonin, R. rubescens - CAS 28957-04-2 - Calbiochem A cell-permeable diterpenoid compound that possesses anti NF-κB activity and displays antiproliferative and antiangiogenic properties. | 5MG | ₹10670 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | O9639 | Oridonin ≥98% (HPLC), solid | 5MG | ₹13964.25 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | O9639 | Oridonin ≥98% (HPLC), solid | 25MG | ₹55737.93 | 2022-06-14 | Buy |
Properties
Melting point :248-250°C
Boiling point :599.8±50.0 °C(Predicted)
Density :1.42±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: >20mg/mL
form :Yellow solid
pka :10.96±0.70(Predicted)
color :White or off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
InChIKey :SDHTXBWLVGWJFT-WNKSEERENA-N
SMILES :O[C@@]12OC[C@]3([C@H](CCC(C)(C)[C@@]3([H])[C@@H]1O)O)[C@]1([H])CC[C@@]3([H])C(=C)C(=O)[C@@]21C3([H])O |&1:1,4,5,11,13,16,20,26,r|
Boiling point :599.8±50.0 °C(Predicted)
Density :1.42±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: >20mg/mL
form :Yellow solid
pka :10.96±0.70(Predicted)
color :White or off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
InChIKey :SDHTXBWLVGWJFT-WNKSEERENA-N
SMILES :O[C@@]12OC[C@]3([C@H](CCC(C)(C)[C@@]3([H])[C@@H]1O)O)[C@]1([H])CC[C@@]3([H])C(=C)C(=O)[C@@]21C3([H])O |&1:1,4,5,11,13,16,20,26,r|
Safety Information
Symbol(GHS): |
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Signal word: | Warning | ||||||||||||||
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Description
A cell-permeable diterpenoid compound that possesses anti NF-κB activity and displays antiproliferative (ED50 ~ 2.7 g/ml in lymphoid malignant cells) and antiangiogenic properties (significantly inhibits network formation of HMEC-1 cells at 2.5 g/ml). Reported to affect DNA synthesis, induce apoptosis and initiate cell cycle arrest. Shown to efficiently block both TNF-α and LPS-induced NF-κB activity in Jurkat and in RAW264.7 murine macrophages, and inhibit p65 NF-κB transcriptional activity (IC50 ~ 5 g/ml in MT-1 cells) by disrupting NF-κB DNA-binding activity without interfering with its nuclear translocation.Related product price
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Suppliers and manufacturers
A.J Chemicals
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