PRIMA-1
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- ₹9049.7 - ₹36047.25
- Product name: PRIMA-1
- CAS: 5608-24-2
- MF: C9H15NO3
- MW: 185.22
- EINECS:
- MDL Number:MFCD19199989
- Synonyms:PRIMA-1;P53 REACTIVATION AND INDUCTION OF MASSIVE APOPTOSIS;2,2-BIS(HYDROXYMETHYL)-1-AZABICYCLO[2,2,2]OCTAN-3-ONE;2,2-BIS(HYDROXYMETHYL)-3-QUINUCLIDINONE;2,2-dimethylolquinuclidin-3-one;7,7-bis(hydroxymethyl)-1-azabicyclo[2.2.2]octan-8-one;PRIMA-1 - CAS 5608-24-2 - Calbiochem;2-Bis(hydroxymethyl)-3-quinuclidinone
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberP0069
- Product descriptionPRIMA-1 ≥98% (HPLC), solid
- Packaging5MG
- Price₹9049.7
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberP0069
- Product descriptionPRIMA-1 ≥98% (HPLC), solid
- Packaging25MG
- Price₹36047.25
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | P0069 | PRIMA-1 ≥98% (HPLC), solid | 5MG | ₹9049.7 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P0069 | PRIMA-1 ≥98% (HPLC), solid | 25MG | ₹36047.25 | 2022-06-14 | Buy |
Properties
Melting point :146-147 °C
Boiling point :353.7±17.0 °C(Predicted)
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,2-8°C
solubility :H2O: >10mg/mL
pka :13.68±0.10(Predicted)
form :solid
color :white to off-white
Water Solubility :Soluble in water at 10mg/ml
Sensitive :Light Sensitive
Boiling point :353.7±17.0 °C(Predicted)
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,2-8°C
solubility :H2O: >10mg/mL
pka :13.68±0.10(Predicted)
form :solid
color :white to off-white
Water Solubility :Soluble in water at 10mg/ml
Sensitive :Light Sensitive
Safety Information
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| Signal word: | Danger | |||||||||||||||||||||
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Description
Mutations in the p53 tumor suppressor are found in many different neoplastic cells. PRIMA-1 restores sequence-specific DNA binding and transactivational activity to mutant p53 proteins at relatively high μM to mM concentrations. It is therefore a unique anti-oncogenic substance, working as a re-activator of the apoptotic function of mutant p53 via conformational modulation of function-specific epitopes. PRIMA-1 represents a novel lead compound which may be further modified to provide more potent therapeutic agents acting via the reactivation mechanism.More related product prices
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