Pifithrin-α (PFTα)
- ₹4800 - ₹23340
- Product name: Pifithrin-α (PFTα)
- CAS: 63208-82-2
- MF: C16H19BrN2OS
- MW: 367.3
- EINECS:
- MDL Number:MFCD00417851
- Synonyms:1-(4-METHYLPHENYL)-2-(4,5,6,7-TETRAHYDRO-2-IMINO-3(2H)-BENZOTHIAZOLYL)ETHANONE, MONOHYDROBROMIDE;Pifithrin-Hydrobromide;2-(2-imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanone hydrobromide;PFT-α,Pifithrin-α;Zinc03874684;Ethanone, 1-(4-Methylphenyl)-2-(4,5,6,7-tetrahydro-2-iMino-3(2H)-benzothiazolyl)-, MonohydrobroMide;PFTα hydrobroMide;Pifithrin-alpha . HBr
6 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 5MG
- 10MG
- 50MG
- ManufacturerTCI Chemicals (India)
- Product numberP2751
- Product descriptionPifithrin-α
- Packaging10MG
- Price₹4800
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberP2751
- Product descriptionPifithrin-α
- Packaging50MG
- Price₹14800
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number506132
- Product descriptionPifithrin-α - CAS 63208-82-2 - Calbiochem A cell-permeable chemical inhibitor of p53.
- Packaging5MG
- Price₹9280.01
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberP4359
- Product descriptionPifithrin-α ≥95% (HPLC), powder
- Packaging5MG
- Price₹14460
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number506132
- Product descriptionPifithrin-α - CAS 63208-82-2 - Calbiochem A cell-permeable chemical inhibitor of p53.
- Packaging10MG
- Price₹21460
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberP4359
- Product descriptionPifithrin-α ≥95% (HPLC), powder
- Packaging10MG
- Price₹23340
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | P2751 | Pifithrin-α | 10MG | ₹4800 | 2022-05-26 | Buy |
TCI Chemicals (India) | P2751 | Pifithrin-α | 50MG | ₹14800 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | 506132 | Pifithrin-α - CAS 63208-82-2 - Calbiochem A cell-permeable chemical inhibitor of p53. | 5MG | ₹9280.01 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | P4359 | Pifithrin-α ≥95% (HPLC), powder | 5MG | ₹14460 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 506132 | Pifithrin-α - CAS 63208-82-2 - Calbiochem A cell-permeable chemical inhibitor of p53. | 10MG | ₹21460 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | P4359 | Pifithrin-α ≥95% (HPLC), powder | 10MG | ₹23340 | 2022-06-14 | Buy |
Properties
Melting point :192.1-192.5 °C(lit.)
storage temp. :-20°C
solubility :DMSO: 20 mg/mL
form :powder
pka :9.11(at 25℃)
color :off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
storage temp. :-20°C
solubility :DMSO: 20 mg/mL
form :powder
pka :9.11(at 25℃)
color :off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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Description
Pifithrin-α is an inactivator of p53 that blocks p53-dependent transcriptional activation and apoptosis. It prevents p53-mediated apoptosis induced by cytotoxic compounds in C8 cells at 10 μM and in human umbilical vein endothelial cells at 30 μM. Pifithrin-α can also protect cells from DNA damage-induced apoptosis by a p53-independent mechanism that might involve cyclin D1.More related product prices
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