Sivelestat
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- ₹11880.01 - ₹52988.38
- Product name: Sivelestat
- CAS: 127373-66-4
- MF: C20H22N2O7S
- MW: 434.46
- EINECS:
- MDL Number:MFCD00889071
- Synonyms:(2-((4-(Pivaloyloxy)phenyl)sulfonamido)benzoyl)glycine;Elastase Inhibitor IV - CAS 127373-66-4 - Calbiochem;EI-546;LY-544349;ONO-5046;CS-1329;EI 546 sodium salt hydrate;Elaspol sodium salt hydrate;LY 544349 sodium salt hydrate;o-(p-Hydroxybenzenesulfonamido)hippuric acid, pivalate (ester) sodium salt hydrate
3 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 1MG
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberS7198
- Product descriptionSivelestat sodium salt hydrate ≥98% (HPLC), solid
- Packaging25MG
- Price₹52988.38
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberS7198
- Product descriptionSivelestat sodium salt hydrate ≥98% (HPLC), solid
- Packaging5MG
- Price₹13130.73
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number324759
- Product descriptionElastase Inhibitor IV - CAS 127373-66-4 - Calbiochem The Elastase Inhibitor IV, also referenced under CAS 127373-66-4, controls the biological activity of Elastase. This small molecule/inhibitor is prima
- Packaging1MG
- Price₹11880.01
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | S7198 | Sivelestat sodium salt hydrate ≥98% (HPLC), solid | 25MG | ₹52988.38 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S7198 | Sivelestat sodium salt hydrate ≥98% (HPLC), solid | 5MG | ₹13130.73 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 324759 | Elastase Inhibitor IV - CAS 127373-66-4 - Calbiochem The Elastase Inhibitor IV, also referenced under CAS 127373-66-4, controls the biological activity of Elastase. This small molecule/inhibitor is prima | 1MG | ₹11880.01 | 2022-06-14 | Buy |
Properties
Melting point :218-220°
Density :1.369±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :3.67±0.10(Predicted)
form :White to off-white solid
color :white to off-white
InChIKey :BTGNGJJLZOIYID-UHFFFAOYSA-N
Density :1.369±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :3.67±0.10(Predicted)
form :White to off-white solid
color :white to off-white
InChIKey :BTGNGJJLZOIYID-UHFFFAOYSA-N
Safety Information
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Description
Sivelestat is a cell-permeable sulfanilide compound that acts as a potent, substrate-competitive, and highly specific inhibitor of neutrophil elastase (IC50 = 19-49 nM in rat, rabbit, hamster, human, and mouse leukocyte elastase). Sivelestat displays >100-fold greater selectivity over pancreas elastase (IC50 = 5.6 μM). Sivelestat does not inhibit trypsin, thrombin, plasmin, kallikrein, chymotrypsin, and cathepsin G even at concentrations as high as 100 μM. Sivelestat effectively suppresses human neutrophil elastase-induced lung hemorrhage and skin capillary permeability. Sivelestat is also reported to inhibit mast cell Stat6-protease.More related product prices
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