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ChemicalBook > Product Catalogue >API >Nervous system drugs >Antidepressants, Antimanics drugs >Trazodone hydrochloride

Trazodone hydrochloride

Trazodone hydrochloride Structure
  • ₹3311.7 - ₹20426.78
  • Product name: Trazodone hydrochloride
  • CAS: 25332-39-2
  • MF: C19H23Cl2N5O
  • MW: 408.32
  • EINECS:246-855-5
  • MDL Number:MFCD00079603
  • Synonyms:TRAZODONE HYDROCHLORIDE;)-onehcl ;2-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-s-triazolo(4,3-a)pyridin-3(2h ;af1161 ;kb-831 ;molipaxin ;pragmazone ;thombran
4 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 500MG
  • 1ML
  • 1G
  • 5G
  • ManufacturerSigma-Aldrich(India)
  • Product numberT-030
  • Product descriptionTrazodone hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant?
  • Packaging1ML
  • Price₹3311.7
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT6154
  • Product descriptionTrazodone hydrochloride ≥99% (HPLC), powder
  • Packaging1G
  • Price₹6959.7
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT6154
  • Product descriptionTrazodone hydrochloride ≥99% (HPLC), powder
  • Packaging5G
  • Price₹13353.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR3372
  • Product descriptionTrazodone Hydrochloride certified reference material, pharmaceutical secondary standard
  • Packaging500MG
  • Price₹20426.78
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) T-030 Trazodone hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant? 1ML ₹3311.7 2022-06-14 Buy
Sigma-Aldrich(India) T6154 Trazodone hydrochloride ≥99% (HPLC), powder 1G ₹6959.7 2022-06-14 Buy
Sigma-Aldrich(India) T6154 Trazodone hydrochloride ≥99% (HPLC), powder 5G ₹13353.3 2022-06-14 Buy
Sigma-Aldrich(India) PHR3372 Trazodone Hydrochloride certified reference material, pharmaceutical secondary standard 500MG ₹20426.78 2022-06-14 Buy

Properties

Melting point :223-226?C
Flash point :9℃
storage temp. :2-8°C
solubility :45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 23.3 mg/mL
form :powder
color :off-white
PH :pH (10g/l, 25℃) : 3.9~4.5
Water Solubility :Soluble at 25mg/ml in methanol. Also soluble in 0.1M HCl or DMSO. Insoluble in water /n
InChIKey :OHHDIOKRWWOXMT-UHFFFAOYSA-N
CAS DataBase Reference :25332-39-2(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Trazodone Hydrochloride belongs to the hydrochloride salt form of trazodone with antidepressant and sedative activities, which is primarily used in the treatment of major depression. It serves as a serotonin uptake inhibitor that is effective for patients suffering from major depressive disorders and other subsets of depressive disorders, which is especially helpful for geriatric patients with severe agitation and certain depressive disorders associated with insomnia and anxiety since it has proved that trazodone also has anti-anxiety (anxiolytic) and sleep-inducing (hypnotic) effects. Besides, it is often prescribed as a sedative that is used for the treatment of panic attacks, aggressive behavior, agoraphobia, and cocaine withdrawal in combination with other drugs. Trazodone Hydrochloride is an oral drug that functions by affecting the balance of chemicals (neurotransmitters) within the brain that nerves use to communicate with (stimulate) each other.

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