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Formoterol fumarate dihydrate

CAS No.: 183814-30-4

Chemical Name:: Formoterol fumarate dihydrate

Synonyms: Formoterol fumarate dihydrate;Unii-W34shf8J2k;Formoterol hemifumar;forMaMide fuMarate dihydrate;Formoterol Fumarate (100 mg);Formoterol fumarate 2-hydrate;Arformoterol Fumarate Dihydrate;Formoterol Hemifumarate Dihydrate;Formoterol hemifumarate monohydrate;Formoterol fumarate dihydrate, >=99%

CBNumber:: CB02130563

Molecular Formula:: C23H28N2O8

Molecular Weight:: 460.48

MOL File:: 183814-30-4.mol

MSDS File:: SDS

Modify Date:: 2024/4/15 18:41:30

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Formoterol fumarate dihydrate Properties

Melting point	116-120°C
storage temp.	2-8°C
solubility	DMSO: soluble20mg/mL
form	solid
color	white to off-white
InChIKey	RATSWNOMCHFQGJ-XODSYJLDSA-N
SMILES	C(/C(=O)O)=C\C(=O)O.[C@@H](C1C=CC(O)=C(NC=O)C=1)(O)CN[C@@H](C)CC1C=CC(OC)=CC=1 \|&1:8,22,r\|
CAS DataBase Reference	183814-30-4

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS08
Signal word	Danger
Hazard statements	H332-H361d-H370-H373-H412
Precautionary statements	P201-P202-P260-P273-P304+P340+P312-P308+P311
RIDADR	UN 2811 6.1 / PGII
WGK Germany	3
HS Code	29242990

Formoterol fumarate dihydrate price More Price(3)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	F9552	Formoterol fumarate dihydrate >98% (HPLC)	183814-30-4	10MG	₹18824.68	2022-06-14	Buy
Sigma-Aldrich(India)	PHR2703	Formoterol Fumarate certified reference material, pharmaceutical secondary standard	183814-30-4	500MG	₹34066.28	2022-06-14	Buy
Sigma-Aldrich(India)	F9552	Formoterol fumarate dihydrate >98% (HPLC)	183814-30-4	50MG	₹74465.18	2022-06-14	Buy

Product number	Packaging	Price	Buy
F9552	10MG	₹18824.68	Buy
PHR2703	500MG	₹34066.28	Buy
F9552	50MG	₹74465.18	Buy

Formoterol fumarate dihydrate Chemical Properties,Uses,Production

Chemical Properties

Pale Yellow Solid

Biological Activity

Potent, selective and long-acting β 2 -adrenoceptor agonist. Displays 330-fold selectivity for β 2 over β 1 receptors (pK d values are 8.12 and 5.58 respectively). Potently relaxes guinea pig trachea (pD 2 = 9.29), and is longer-acting and 100-fold more potent than salbutamol.

Drug interactions

The efficacy and tolerability of glycopyrronium/formoterol fumarate metered dose inhaler, a fixed-dose combination of glycopyrronium/formoterol fumarate dihydrate 14.4/10 μg (equivalent to glycopyrrolate/formoterol fumarate 18/9.6 μg) delivered by metered dose inhaler using innovative co-suspension delivery technology, was investigated in patients (n = 292) with COPD [12C]. There were no meaningful pharmacokinetic interactions, whether drug–drug or due to formulation, between glycopyrronium and formoterol following treatment with formulated using a new co-suspension delivery technology. The incidence of cardiovascular events of special interest was low (stroke, 0%–0.4%; cardiac ischemia, 0.4%–2.3%; cardiac failure, 1.3%–2.5%; arrhythmia, 1.3%–3.2%), and no important trends in clinical laboratory results, vital signs, or electrocardiograms were observed[1].

References

[1] Aagaard, Lise . "A worldwide yearly survey of new data in adverse drug reactions." (2014).

Formoterol fumarate dihydrate Preparation Products And Raw materials

Raw materials

Preparation Products

Formoterol fumarate dihydrate Suppliers

Global( 205)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
AARTI INDUSTRIES LIMITED	912267976666	New Delhi, India	172	58	Inquiry
Micro Orgo Chem	+91-91-022-24969510 +91-9082984052	Mumbai, India	66	58	Inquiry
Alkaloids Private Limited	+91-9866110664 +91-9866110664	Telangana, India	25	58	Inquiry
Ralington Pharma	+91-7948911722 +91-9687771722	Gujarat, India	1350	58	Inquiry
Jayco Chemical Industries	+91-22-28458881 +91-2228458881	Maharashtra, India	30	58	Inquiry
Vamsi Labs Ltd	+91-2172357274 +91-9891966300	Maharashtra, India	43	58	Inquiry
Cipla Ltd	+912224826000	Maharashtra, India	133	58	Inquiry
SynZeal Research Pvt Ltd	+1 226-802-2078	Gujarat, India	6522	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
Pharma Affiliates	172-5066494	Haryana, India	6761	58	Inquiry

Supplier	Advantage
AARTI INDUSTRIES LIMITED	58
Micro Orgo Chem	58
Alkaloids Private Limited	58
Ralington Pharma	58
Jayco Chemical Industries	58
Vamsi Labs Ltd	58
Cipla Ltd	58
SynZeal Research Pvt Ltd	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
Pharma Affiliates	58

183814-30-4(Formoterol fumarate dihydrate)Related Search:

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FUMARATE Formoterol fumarate dihydrate

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Formamide, N-(2-hydroxy-5-((1R)-1-hydroxy-2-(((1R)-2-(4-methoxyphenyl)-1-methylethyl)amino)ethyl)phenyl)-, rel-, (2E)-2-butenedioate (2:1) (salt), dihydrate Unii-W34shf8J2k (±)-(R,R)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamidehemifumarate Formoterol fumarate dihydrate ,98.5% (r*,r*)-n-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide fumarate dihydrate Formoterol Fumarate (100 mg) forMaMide fuMarate dihydrate N-(2-hydroxy-5-((R)-1-hydroxy-2-(((R)-1-(4-Methoxyphenyl)propan-2-yl)aMino)ethyl)phenyl)forMaMide fuMarate dihydrate Formoterol fumarate dihydrate, >=99% (R*,R*)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide fumarate dihydrateChemicalBook R*)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide fumarate dihydrate Formoterol hemifumarate monohydrate Formoterol fumarate dihydrate Solution in Methanol, 100μg/mL Formoterol Fumarate Monohydrate/ dihydrate Formoterol hemifumar Formoterol fumarate dihydrateQ: What is Formoterol fumarate dihydrate Q: What is the CAS Number of Formoterol fumarate dihydrate Q: What is the storage condition of Formoterol fumarate dihydrate Formoterol fumarate N-(2-hydroxy-5-(1-hydroxy-2-((1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)phenyl)formamide fumarate dehydrate Formoterol fumarate dihydrate Formoterol fumarate 2-hydrate Formoterol hemifumarate salt monohydrate Formoterol fumarate N-(2-hydroxy-5-(1-hydroxy-2-((1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)phenyl)formamide fumarate dehydrate Arformoterol Fumarate Dihydrate Formoterol Hemifumarate Dihydrate 183814-30-4 183818-30-4 C19H24N2O4189C4H4O4 C23H32N2O10 C42H52N4O122H2O Other APIs API Aromatics Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals