Fluvastatin sodium salt
- CAS No.
- 93957-55-2
- Chemical Name:
- Fluvastatin sodium salt
- Synonyms
- FLUVASTATIN;FLUVASTATIN SODIUM;Flurastatin Sodium;Fluvastatin sodium hydrate;xu62-320;3-cs/ex-PinD;fluindostatin;FLUVASTATIN NA;(+)-Pinanediol;XU 62320 sodium
- CBNumber:
- CB0231286
- Molecular Formula:
- C24H25FNNaO4
- Molecular Weight:
- 433.45
- MOL File:
- 93957-55-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/5/22 11:23:49
| Melting point | 194-197°C |
|---|---|
| storage temp. | 2-8°C |
| solubility | H2O: ≥9mg/mL |
| form | powder |
| color | white to tan |
| Merck | 14,4218 |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months. |
| InChIKey | ZGGHKIMDNBDHJB-RPQBTBOMSA-M |
| CAS DataBase Reference | 93957-55-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | MJ9675050 | |||||||||
| HS Code | 2933995300 | |||||||||
| NFPA 704 |
|
Fluvastatin sodium salt price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML0038 | Fluvastatin sodium hydrate ≥98% (HPLC) | 93957-55-2 | 10MG | ₹10207.98 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML0038 | Fluvastatin sodium hydrate ≥98% (HPLC) | 93957-55-2 | 50MG | ₹39143.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR1620 | Fluvastatin sodium Pharmaceutical Secondary Standard; Certified Reference Material | 93957-55-2 | 1G | ₹10792.53 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 344096 | InSolution Fluvastatin, Sodium Salt - CAS 93957-55-2 - Calbiochem A synthetic, competitive inhibitor of HMG-CoA reductase that acts as anti-hypercholesterolemic agent. | 93957-55-2 | 10MG | ₹10390 | 2022-06-14 | Buy |
| TCI Chemicals (India) | F0820 | Fluvastatin Sodium Salt | 93957-55-2 | 1G | ₹9700 | 2022-05-26 | Buy |
Fluvastatin sodium salt Chemical Properties,Uses,Production
Description
Fluvastatin sodium is the fourth HMG-CoA reductase inhibitor to reach the market as a dietary adjunct for lowing total and low-density lipoprotein (LDL) cholesterol. Fluvastatin sodium is the first totally synthetic inhibitor of its class and has more potent effects on reducing serum total and LDL cholesterol and serum triglyceride levels than compactin or lovastatin. Moreover, fluvastatin exhibits a unique set of pharmacological properties including a biopharmaceutical profile most consistent with hepatoselectivity. It has been reported to be well tolerated and to exhibit a safety profile superior to other agents of its class. The main mechanism by which HMG-CoA reductase inhibitors lower plasma cholesterol has been suggested to be up-regulation of hepatocellular LDL-receptor expression and enhancement of receptor-mediated clearance and catabolism of LDL cholesterol.
Chemical Properties
Yellow Powder
Uses
Fluvastatin-d6 Sodium Salt is the labeled analogue of Fluvastatin Sodium Salt (F601250), a synthetic HMG-CoA reductase inhibitor. Antilipemic.
General Description
Fluvastatin sodium is a lipid-lowering drug that belongs to the group of compounds known as statins. It acts by inhibiting the enzyme HMG-CoA reductase that plays a key role in the cholesterol production. It is generally used to reduce plasma cholesterol levels and prevent cardiovascular disease.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Biological Activity
Orally active, potent and competitive HMG-CoA reductase inhibitor (IC 50 = 40 -100 nM at human liver microsomes). Inhibits vascular smooth muscle proliferation in vitro (IC 50 = 70 nM) and exhibits antihypercholesterolemic and antioxidant activity in vivo .
Fluvastatin sodium salt Preparation Products And Raw materials
Raw materials
1of3
chevron_rightPreparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Aurobindo Pharma Limited | +914066725000 | Telangana, India | 112 | 58 | Inquiry |
| Hetero Drugs Limited | +91-4023704923 +91-4023704923 | Telangana, India | 296 | 58 | Inquiry |
| Sun Pharmaceutical Industries Ltd | +91-2242244224 +91-2243244324 | Maharashtra, India | 108 | 58 | Inquiry |
| M S Pharmachem | 91-22-32910305 | Maharashtra, India | 56 | 58 | Inquiry |
| Indogulf Group | 91-22-23455220 | Maharashtra, India | 249 | 58 | Inquiry |
| Hetero Drugs Limited | 08048372500Ext 439 | Hyderabad, India | 174 | 58 | Inquiry |
| Rushi Healthcare Pvt., Ltd. | 91-22-26200440 | Maharashtra, India | 50 | 58 | Inquiry |
| Apan Imex Private Limited | 91-79-26850087 | Gujarat, India | 31 | 58 | Inquiry |
| Sai Prathyu Marketing | 91-9666672409 | Hyderabad, India | 162 | 58 | Inquiry |
| Ranbaxy Laboratories Limited | (+91 22) 4324 4324 | New Delhi, India | 76 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Aurobindo Pharma Limited | 58 |
| Hetero Drugs Limited | 58 |
| Sun Pharmaceutical Industries Ltd | 58 |
| M S Pharmachem | 58 |
| Indogulf Group | 58 |
| Hetero Drugs Limited | 58 |
| Rushi Healthcare Pvt., Ltd. | 58 |
| Apan Imex Private Limited | 58 |
| Sai Prathyu Marketing | 58 |
| Ranbaxy Laboratories Limited | 58 |