ChemicalBook > Product Catalog >API >Circulatory system drugs >Lipid regulating drugs >Pravastatin sodium
Pravastatin sodium
- CAS No.
- 81131-70-6
- Chemical Name:
- Pravastatin sodium
- Synonyms
- Prava;cs-514;Vasten;ELISOR;Lipidal;sq31000;Liprevil;Pravacol;Pravasin;Selipran
- CBNumber:
- CB9317123
- Molecular Formula:
- C23H36NaO7
- Molecular Weight:
- 447.52
- MOL File:
- 81131-70-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/30 15:45:59
| Melting point | 171.2-173 °C |
|---|---|
| storage temp. | 2-8°C |
| solubility | H2O: 19 mg/mL |
| form | powder |
| color | white |
| Merck | 14,7714 |
| BCS Class | 1 (CLogP), 3 (LogP) |
| Stability | Hygroscopic |
| CAS DataBase Reference | 81131-70-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P332+P313-P337+P313-P362-P403+P233-P405-P501 |
| Hazard Codes | F,C |
| Risk Statements | 11-34 |
| Safety Statements | 16-26-36/37/39-45 |
| RIDADR | 3077 |
| WGK Germany | 2 |
| RTECS | QJ7185000 |
| HazardClass | 9 |
| PackingGroup | III |
| HS Code | 29329990 |
Pravastatin sodium price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | P4498 | Pravastatin sodium salt hydrate ≥98% (HPLC), powder | 81131-70-6 | 25MG | ₹9147.13 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 524403 | Pravastatin, Sodium Salt - CAS 81131-70-6 - Calbiochem A water-soluble, competitive 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that potently blocks in vivo cholesterol synthesis (K | 81131-70-6 | 25MG | ₹14260 | 2022-06-14 | Buy |
| TCI Chemicals (India) | P1796 | Pravastatin Sodium | 81131-70-6 | 100MG | ₹10800 | 2022-05-26 | Buy |
| TCI Chemicals (India) | P1796 | Pravastatin Sodium | 81131-70-6 | 500MG | ₹14500 | 2022-05-26 | Buy |
Pravastatin sodium Chemical Properties,Uses,Production
Chemical Properties
White Crystalline Powder
Uses
Pravastatin sodium is the salt of pravastatin, a ring-opened member of the statin family. Pravastatin is produced biosynthetically from compactin (mevastatin) by a number of microorganisms, notably Absidia, Cunninghamella, Syncephalastrum, Nocardia or Streptomyces. Typically, statins like compactin, lovastatin and simvastatin possess a β-hydroxy lactone ring which is a pro-drug for the readily ring-opened dihydroxyacid generally regarded as the active HMG-CoAreductase inhibitor. Importantly, the free carboxylic acid enables pravastatin to be freely water soluble within biological pH ranges.
Definition
ChEBI: An organic sodium salt that is the sodium salt of pravastatin. A reversible inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA), it is used for lowering cholesterol and preventing cardiovascular disease. It is one of the lower potency statins, but has the advantage of fewer side effects compared with lovastatin and simvastatin.
General Description
A water-soluble, competitive 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that potently blocks in vivo cholesterol synthesis (Ki = ~1 nM). Offers cardioprotection. Also acts as an immunomodulator and an inhibitor of ras p21 isoprenylation.
Biological Activity
Water-soluble, competitive inhibitor of 3-hydroxy-3-methyl coenzyme A (HMG-CoA) reductase. Potently blocks cholesterol synthesis in vivo (K i ~ 1 nM) and displays cardioprotective properties.
Pravastatin sodium Preparation Products And Raw materials
Global( 376)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Concord Biotech Limited | +91-2714398200 +91-2714398200 | Gujarat, India | 22 | 58 | Inquiry |
| Apotex Pharmachem India Pvt Ltd | +91-8022891034 +91-8022891000 | Karnataka, India | 109 | 58 | Inquiry |
| Vervain Pharm Chem | 91-22-66950648 | Maharashtra, India | 139 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Indogulf Group | 91-22-23455220 | Maharashtra, India | 249 | 58 | Inquiry |
| Euroasia Trans Continental | +91 22 56349035-36 | New Delhi, India | 519 | 47 | Inquiry |
| Prism Consultancy | 91-9825119804 | Gujarat, India | 66 | 58 | Inquiry |
| Jai Radhe Sales | 0091-79-26431096 | New Delhi, India | 157 | 57 | Inquiry |
| M S Pharmachem | 91-22-32910305 | Maharashtra, India | 56 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Concord Biotech Limited | 58 |
| Apotex Pharmachem India Pvt Ltd | 58 |
| Vervain Pharm Chem | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| A.J Chemicals | 58 |
| Indogulf Group | 58 |
| Euroasia Trans Continental | 47 |
| Prism Consultancy | 58 |
| Jai Radhe Sales | 57 |
| M S Pharmachem | 58 |
81131-70-6(Pravastatin sodium)Related Search:
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2-alpha,6-alpha,8-beta(r*),8a-alpha))-*
cs-514
Eptastatin
1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-.beta.,.delta.,6-trihydroxy-2-methyl-8-(2S)-2-methyl-1-oxobutoxy-, monosodium salt, (.beta.R,.delta.R,1S,2S,6S,8S,8aR)-
(βr, δr,1s,2s,6s,8s,8ar)-1,2,6,7,8,8a-hexahydro-β, δ,6-trihydroxy-2-methyl-8[(2s)-2-methyl-1-oxobutoxyl]-1-naphthaleneheptanoic acid sodium
1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-b,d,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-, monosodium salt, [1S-[1a(bS*,dS*),2a,6a,8b(R*),8aa]]-
1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-b,d,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-, monosodium salt, (bR,dR,1S,2S,6S,8S,8aR)- (9CI)
3b-Hydroxycompactin sodium salt
Lipidal
Liprevil
Oliprevin
Prava
Pravacol
Pravasin
Pravasine
Selektine
Selipran
Vasten
Paravastatin
PravastatinNaC23H35Na07
1-Naphthaleneheptanoicacid
Pravastatine
Pravastatinesodium
Pravastatin Sodium (US Pat 1981)
Elisor, Kopostat, Mevalotin, Pravachol, Pravaselect,
[1S-[1a(bS,dS),2a,6b,8b(R),8aa]]-1,2,6,7,8,8a-Hexahydro-b,d,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphthaleneheptanoic acid monosodium salt
Pravastatinsodium,(S)
(R,dR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-,d,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic Acid Sodium Salt
sodiuM (3R,5R)-3,5-dihydroxy-7-((1S,2S,6S,8S,8aR)-6-hydroxy-2-Methyl-8-(((S)-2-Methylbutanoyl)oxy)-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)heptanoate
Pravastatin sodiuM salt hydrate
CS-514 Sodium
(βR, δR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β, δ,6-trihydroxy-2-methyl-8[(2S)-2-methyl-1-oxobutoxyl]-1-naphthaleneheptanoic acid sodium hydrate
Eptastatin sodium salt hydrate
Mevalotin, CS 514, SQ 3100
Pravastatin sodium, >=98%
[1S-[1a(bS,dS),2a,6b,8b(R),8aa]]-1,2,6,7,8,8a-Hexahydro-b,d,6-tri
ELISOR
EPTASTATIN SODIUM
(BETA R,DELTA R,1S,2S,6S,8S,8AR)-1,2,6,7,8,8A-HEXAHYDRO-BETA,DELTA,6-TRIHYDROXY-2-METHYL-8-[(2S)-2-METHYL-1-OXOBUTOXY]-1-NAPHTHALENEHEPTANOIC ACID MONOSODIUM SALT
(BETAR, DELTAR,1S,2S,6S,8S,8AR)-1,2,6,7,8,8A-HEXAHYDRO-BETA, DELTA,6-TRIHYDROXY-2-METHYL-8[(2S)-2-METHYL-1-OXOBUTOXYL]-1-NAPHTHALENEHEPTANOIC ACID SODIUM
(BETA-R,DELTA-R,1S,2S,6S,8S,8AR)-1,2,6,7,8,8A-HEXAHYDRO-BETA,DELTA,6-TRIHYDROXY-2-METHYL-8[(2S)-2-METHYL-1-OXOBUTOXYL]-1-NAPHTHALENEHEPTANOIC ACID NA
epastatinsodium
lipostat
sq31000
utoxy)-beta,delta,6-trihydroxy-,monosodiumsalt,(1s-(1-alpha(beta-s*,delta-s
KOPOSTAT
MEVALOTIN
3BETA-HYDROXYCOMPACTIN, NA
PRAVASTATIN SODIUM SALT
PRAVASTATIN SODIUM
PRAVASELECT
PRAVACHOL
Eptastatin sodium salt, (βR, δR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β, δ,6-trihydroxy-2-methyl-8[(2S)-2-methyl-1-oxobutoxyl]-1-naphthaleneheptanoic acid sodium
(betaR,deltaR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-beta,delta,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid monosodium salt
(1S,βR,δR)-1,2,6,7,8,8aβ-Hexahydro-β,δ,6β-trihydroxy-2β-methyl-8α-[[(S)-2-methyl-1-oxobutyl]oxy]-1β-naphthaleneheptanoic acid sodium salt
Pravastatin SodiuM, EP
Pravastatin-d3
Pravastatin-d9 (raceMic)