iproniazid
- CAS No.
- 54-92-2
- Chemical Name:
- iproniazid
- Synonyms
- IPRAZID;Marsilid;iproniazid;Iproniazid>n’-isopropylisonicotinohydrazide;1-Isonicotinoyl-2-isopropylhydrazine;N'-Isopropylpyridine-4-Carbohydrazide;Isonicotinic Acid 2-Isopropylhydrazide;N'-propan-2-ylpyridine-4-carbohydrazide;Isonicotinic acid N'-isopropyl-hydrazide
- CBNumber:
- CB0928533
- Molecular Formula:
- C9H13N3O
- Molecular Weight:
- 179.22
- MOL File:
- 54-92-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/18 11:31:13
| Melting point | 112.5-113.5° |
|---|---|
| Boiling point | 311.75°C (rough estimate) |
| Density | 1.1305 (rough estimate) |
| refractive index | 1.5100 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 11.28±0.23(Predicted) |
| form | Solid |
| color | Pale Beige |
| CAS DataBase Reference | 54-92-2 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P501-P270-P264-P301+P312+P330 |
| HS Code | 2933399990 |
| Toxicity | An isopropyl derivative of isoniazid that was found to have mood-elevating effects in tuberculosis patients. It was later found to be a monoamine oxidase (MAO) inhibitor and, although not currently approved for clinical use as an antidepressant due to its propensity to cause liver damage it led to the development of other MAO inhibitors currently in use. In addition to hepatotoxic effects, iproniazid is a hypotensive agent and can cause potentially hazardous reactions with other drugs and amine-rich foods. |
iproniazid price More Price(2)
iproniazid Chemical Properties,Uses,Production
Uses
Iproniazid is a hydrazine based drug used as an antidepressant. Iproniazid acts as an irreversible and nonselective monoamine oxidase inhibitor.
World Health Organization (WHO)
Iproniazid, a monoamine oxidase inhibitor (MAOI), was introduced in 1952 for the treatment of depressive illness. Subsequently concern regarding potentially serious interactions between MAOIs and foods containing tyramine inspired much restrictive regulatory action. However, MAOIs still retain a place in the treatment of serious depressive illness although there is no international consensus on which compounds should be preferred. Thus iproniazid remains available in several countries.
Purification Methods
Crystallise it from *benzene or *benzene /pet ether and dry it in a vacuum. It is soluble in H2O and EtOH. [Fox & Gibas J Org Chem 18 994 1953.] The dihydrochloride has m 227-228o (from EtOH). [Beilstein 22 III/IV 551.] It is an antidepressant.
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
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| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | China | 1807 | 55 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32836 | 60 | Inquiry |
| Accela ChemBio Inc. | +1-858-6993322 | United States | 19479 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29825 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
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