ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Piperazine compounds >1-Acetylpiperazine
1-Acetylpiperazine
- CAS No.
- 13889-98-0
- Chemical Name:
- 1-Acetylpiperazine
- Synonyms
- N-ACETYLPIPERAZINE;1-AcetyL;AKOS BB-5737;acetylpiperazine;N-aetylpiperazine;1-ACETYLPIPERAZINE;N-ACETY PIPERAZINE;n-acetyl ptperazine;1-Piperazinoethanone;Olaparib Impurity 61
- CBNumber:
- CB1717961
- Molecular Formula:
- C6H12N2O
- Molecular Weight:
- 128.17
- MOL File:
- 13889-98-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/8/16 18:05:29
| Melting point | 31-34 °C (lit.) |
|---|---|
| Boiling point | 127 °C |
| Density | 1.0754 (rough estimate) |
| refractive index | 1.4880 (estimate) |
| Flash point | >230 °F |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | methanol: soluble1g/10 mL, clear, colorless to faintly greenish-yellow |
| form | Liquid After Melting |
| pka | 8.50±0.10(Predicted) |
| color | Clear light yellow |
| Water Solubility | Soluble in water 210 g/L (20°C). |
| Sensitive | Hygroscopic |
| BRN | 112220 |
| CAS DataBase Reference | 13889-98-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS05,GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H314-H334-H335 | |||||||||
| Precautionary statements | P261-P301+P312+P330-P303+P361+P353-P304+P340+P312-P305+P351+P338-P342+P311 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/38-36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 3-10-34 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29339900 | |||||||||
| NFPA 704 |
|
1-Acetylpiperazine price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 359513 | 1-Acetylpiperazine 99% | 13889-98-0 | 5G | ₹3572.25 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 359513 | 1-Acetylpiperazine 99% | 13889-98-0 | 25G | ₹9774.98 | 2022-06-14 | Buy |
| ALFA India | ALF-B20200-30 | 1-Acetylpiperazine, 98% | 13889-98-0 | 250g | ₹20871 | 2022-05-26 | Buy |
| ALFA India | ALF-B20200-22 | 1-Acetylpiperazine, 98% | 13889-98-0 | 100g | ₹25958 | 2022-05-26 | Buy |
| ALFA India | ALF-B20200-14 | 1-Acetylpiperazine, 98% | 13889-98-0 | 25g | ₹6898 | 2022-05-26 | Buy |
1-Acetylpiperazine Chemical Properties,Uses,Production
Chemical Properties
clear light yellow liquid after melting
Uses
1-Acetylpiperazine may be used in the synthesis of series of 7-alkoxyl substituted indolizinoquinoline-5,12-dione derivatives and 2-substituted-N-(naphth-1-ylmethyl)-pyrimidin-4-amines and 2-substituted-N-benzhydrylpyrimidin-4-amines.
General Description
Infrared and Raman spectra of 1-acetylpiperazine have been recorded in the region of 4000-40cm-1.
Purification Methods
Purify 1-acetylpiperazine by recrystallisation from 40% aqueous EtOH or from EtOH/Et2O. It is an irritant, and is hygroscopic. The hydrochloride has m 191o (from EtOH), and the tosylate salt has m 148-149o (from EtOH/EtOAc, 1:16). The free base, however, cannot be isolated by basifying the tosylate salt and extraction with CH2Cl2. [Jacobi Chem Ber 66 113 1933, Mosher et al. J Am Chem Soc 75 4949 1953, Hall J Am Chem Soc 78 2570 1956, Beilstein 23 IV 1786.]
1-Acetylpiperazine Preparation Products And Raw materials
Raw materials
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Global( 351)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| GLR Innovations | +91 9891111994 | New Delhi, India | 4542 | 58 | Inquiry |
| Allchem Lifescience Pvt. Ltd | +919867655500 | Gujarat, India | 971 | 58 | Inquiry |
| Suven Pharmaceuticals Limited | +91-91-40-23541142 +91-4023541142 | Telangana, India | 218 | 58 | Inquiry |
| CNS CHEMICALS | +91-9381957258 +91-9381957258 | Telangana, India | 354 | 58 | Inquiry |
| PVR Life Sciences | +91-9393797870 +91-9000984800 | Telangana, India | 38 | 58 | Inquiry |
| Darshan Pharma Chem | +91-8460053621 +91-9924796811 | Gujarat, India | 42 | 58 | Inquiry |
| Sri Neelima Laboratories | +91-7981733602 +91-9849736989 | Telangana, India | 205 | 58 | Inquiry |
| Shambhavi Enterprises | +91 251 2212444 | Mumbai, India | 54 | 58 | Inquiry |
| P C Chem | +91-8046061281 | Mumbai, India | 676 | 58 | Inquiry |
| Zandu Chemicals Limited | +91 22 2430 7021 | Mumbai, India | 19 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| GLR Innovations | 58 |
| Allchem Lifescience Pvt. Ltd | 58 |
| Suven Pharmaceuticals Limited | 58 |
| CNS CHEMICALS | 58 |
| PVR Life Sciences | 58 |
| Darshan Pharma Chem | 58 |
| Sri Neelima Laboratories | 58 |
| Shambhavi Enterprises | 58 |
| P C Chem | 58 |
| Zandu Chemicals Limited | 58 |
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1-Acetylpiperazine >
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1-acetylpiperazine 13889-98-0
1-ACETYLPIPERAZINE For Synthesis
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