Azelnidipine
![Azelnidipine Structure](CAS/GIF/123524-52-7.gif)
- CAS No.
- 123524-52-7
- Chemical Name:
- Azelnidipine
- Synonyms
- CS-905;CS-499;RS-9054;Calblock;Azelpine;Azedipine;Azelidipine;Azenildipine;AZELNIDIPINE;AZELINIDIPINE
- CBNumber:
- CB1781980
- Molecular Formula:
- C33H34N4O6
- Molecular Weight:
- 582.65
- MOL File:
- 123524-52-7.mol
- Modify Date:
- 2024/4/18 11:58:16
Melting point | 120-126°C |
---|---|
Boiling point | 709.3±60.0 °C(Predicted) |
Density | 1.33±0.1 g/cm3(Predicted) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | DMSO: >10mg/mL |
pka | 7.89(at 25℃) |
form | powder |
color | Yellow |
Merck | 14,907 |
InChIKey | ZKFQEACEUNWPMT-UHFFFAOYSA-N |
CAS DataBase Reference | 123524-52-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() GHS05,GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H302-H318 | |||||||||
Precautionary statements | P280-P301+P312+P330-P305+P351+P338+P310 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 22-41 | |||||||||
Safety Statements | 26-39 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | US7968332 | |||||||||
HS Code | 2933.79.1500 | |||||||||
Toxicity | LD50 in female, male mice, female, male rats (mg/kg): 785, 979, 1267, 1971 orally | |||||||||
NFPA 704 |
|
Azelnidipine price More Price(4)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | A7106 | Azelnidipine ≥98% (HPLC), powder | 123524-52-7 | 10MG | ₹15631.3 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A7106 | Azelnidipine ≥98% (HPLC), powder | 123524-52-7 | 50MG | ₹74551.78 | 2022-06-14 | Buy |
TCI Chemicals (India) | A2433 | Azelnidipine | 123524-52-7 | 1G | ₹7500 | 2022-05-26 | Buy |
TCI Chemicals (India) | A2433 | Azelnidipine | 123524-52-7 | 5G | ₹14500 | 2022-05-26 | Buy |
Azelnidipine Chemical Properties,Uses,Production
Chemical Properties
Yellow Solid
Uses
Azelnidipine is a dihydropyridine calcium channel blocker with antihypertensice activity. Azelnidipine is used for treating ischemic heart disease and cardiac remodeling after myocardial infarction. S tudies show that Azelnidipine ttreatment can reduce the risk of hyperglycemia induced metabolic disorders
Application
Azelnidipine is a novel dihydropyridine derivative, a L-type calcium channel blocker, and an antihypertensive. Acute administration of azelnidipine prevents a sudden drop of cardiac function after acute stress. Azelnidipine may have a protective role in inflammation associated with atherosclerosis.
Biological Activity
Azelnidipine, a novel dihydropyridine derivative, is a L-type calcium channel blocker and antihypertensive. Unlike other L-type calcium channel blockers, azelnidipine causes minimal stimulation of the sympathetic nervous system despite its significant depressor effect. Azelnidipine may have a protective role in inflammation in atherosclerosis.
Azelnidipine Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Anant Pharmaceuticals Pvt Ltd | +91-8550986868 +91-9485998001 | Haryana, India | 461 | 58 | Inquiry |
Honour Lab Limited | +919845977466 | Telangana, India | 164 | 58 | Inquiry |
Hetero Drugs Limited | +91-4023704923 +91-4023704923 | Telangana, India | 296 | 58 | Inquiry |
Precise Biopharma Pvt Ltd | +91-2267828600 +91-2267828600 | Maharashtra, India | 46 | 58 | Inquiry |
Afton Pharma | +91-9712000202 +91-9712000202 | Gujarat, India | 63 | 58 | Inquiry |
Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
Sudarshan Pharma Industries Limited. | 91-22-42221111 | Maharashtra, India | 158 | 58 | Inquiry |
Indexim International | 08048971004 | Gujarat, India | 112 | 58 | Inquiry |
Oceanic Pharmachem Pvt. Ltd. | 91-22-42128600 | Maharashtra, India | 2006 | 58 | Inquiry |
Afton Pharma | 91-9712000202 | Gujarat, India | 40 | 58 | Inquiry |
Supplier | Advantage |
---|---|
Anant Pharmaceuticals Pvt Ltd | 58 |
Honour Lab Limited | 58 |
Hetero Drugs Limited | 58 |
Precise Biopharma Pvt Ltd | 58 |
Afton Pharma | 58 |
Ralington Pharma | 58 |
Sudarshan Pharma Industries Limited. | 58 |
Indexim International | 58 |
Oceanic Pharmachem Pvt. Ltd. | 58 |
Afton Pharma | 58 |
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