Pravastatin Lactone

Pravastatin Lactone Structure
CAS No.
85956-22-5
Chemical Name:
Pravastatin Lactone
Synonyms
Pravastatin EP IMpurity D;R 414;SQ 31369;Pravastatin IMpurity D;PRAVASTATIN SODIUM(RG);Pravastatin class ester;Pravastatin Lactone_x000b_;Pravastatin Sodium EP Impurity D;(1S,3S,7S,8S,8aR)-3-Hydroxy-8-[2-[(;Pravastatin EP Impurity D (Pravastatin Lactone)
CBNumber:
CB31176705
Molecular Formula:
C23H34O6
Molecular Weight:
406.51
MOL File:
85956-22-5.mol
Modify Date:
2023/6/8 9:02:51

Pravastatin Lactone Properties

Melting point 140-143°C
Boiling point 590.5±50.0 °C(Predicted)
Density 1.18±0.1 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility DMF: 25 mg/ml; DMSO: 20 mg/ml; Ethanol: 12.5 mg/ml; PBS (pH 7.2): 10 mg/ml
form A crystalline solid
pka 13.49±0.40(Predicted)
Stability Hygroscopic
CAS DataBase Reference 85956-22-5

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
NFPA 704
0
2 0

Pravastatin Lactone Chemical Properties,Uses,Production

Chemical Properties

White Crystalline Powder

Uses

Pravastatin Lactone is a metabolite of Pravastatin (P702000).

Pravastatin Lactone Preparation Products And Raw materials

Raw materials

Preparation Products

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(2S)-2-Methyl-Butanoic Acid (1S,3S,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3-hydroxy-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester R 414 (1S)-1β-[2-[[(2R,4R)-3,4,5,6-Tetrahydro-4β-hydroxy-6-oxo-2H-pyran]-2-yl]ethyl]-1,2,6,7,8,8aβ-hexahydro-2β-methyl-8α-[[(S)-2-methyl-1-oxobutyl]oxy]naphthalen-6β-ol PRAVASTATIN SODIUM(RG) Pravastatin IMpurity D SQ 31369 Pravastatin class ester (1S,3S,7S,8S,8aR)-3-Hydroxy-8-[2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate [(1S,3S,7S,8S,8aR)-3-hydroxy-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate (1S,3S,7S,8S,8aR)-3-Hydroxy-8-(2-((2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (S)-2-methylbutanoate Pravastatin Sodium Impurity Ⅲ:Pravastatin EP Impurity D (Pravastatin Lactone) Pravastatin Impurity 4(Pravastatin EP Impurity D) (1S,3S,7S,8S,8aR)-3-Hydroxy-8-[2-[( Butanoic acid, 2-methyl-, (1S,3S,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3-hydroxy-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester, (2S)- Pravastatin EP Impurity D (Pravastatin Lactone) Pravastatin Lactone_x000b_ Pravastatin LactoneQ: What is Pravastatin Lactone Q: What is the CAS Number of Pravastatin Lactone Q: What is the storage condition of Pravastatin Lactone Pravastatin Sodium Impurity Ⅲ:Pravastatin EP Impurity D (Pravastatin Lactone) Pravastatin EP IMpurity D Pravastatin Sodium EP Impurity D 85956-22-5 Chiral Reagents Heterocycles Various Metabolites and Impurities Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals